21 January 2025 : Original article
A New Routine Immunity Score (RIS2020) to Predict Severe Infection in Solid-Organ Transplant Recipients
Elizabeth Sarmiento
12ABCDEF, Ikram Ezzahouri13BEF, Maricela Jimenez-Lopez 1ABEF, Kristofer M. Limay Carré1BCDE, Rocio Alonso13B, Carlos Ortiz-Bautista 456B, Magdalena Salcedo Plaza 7B, Maria Luisa Rodríguez-Ferrero 8B, Pedro Martin Padilla-Machaca 9B, Ana Cerron9B, Jose Carlos Chaman9BD, Ana P. Vionnet Salvo310B, Javier Carbone 13101112ABCDEFG*
DOI: 10.12659/AOT.946233
Ann Transplant 2025; 30:e946233
Table 4 Multivariate logistic regression to evaluate the RIS2020 after adjustment for immunological biomarkers.
| Adjustment | RIS2020 Score | Variable of adjustment | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| IgG | 3.893 | 2.115–7.165 | <0.001 | 1.758 | 0.937–3.299 | 0.079 |
| C3 | 4.494 | 2.594–7.788 | <0.001 | 1.327 | 0.619–2.847 | 0.467 |
| CD4 | 3.263 | 1.841–5.784 | <0.001 | 0.928 | 0.437–1.969 | 0.845 |
| CRP | 3.542 | 1.948–6.441 | <0.001 | 1.090 | 0.517–2.30 | 0.821 |
| IgG – serum IgG | ||||||