Living Donor Liver Transplantation with Small Left Lobe Grafts: Prospective Validation of Utility of Splenectomy in Selected Recipients

14 January 2025 : Original article

Hajime Matsushima^1ABCDEF*, Akihiko Soyama

^1BCD, Takanobu Hara

^1BCD, Takashi Hamada

^1BCD, Yuta Kawaguchi^1BCD, Kazushige Migita^1BCD, Ayaka Satoh^1BCD, Yamashita Mampei

^1BCD, Hajime Imamura

^1BCD, Ayaka Kinoshita^1BCD, Tomohiko Adachi^1BCD, Susumu Eguchi^1BCD

DOI: 10.12659/AOT.946374

Ann Transplant 2025; 30:e946374

Introduction Material and Methods Results Discussion Conclusions References

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Table 2 Incidence rates of early allograft dysfunction and small-for-size syndrome.

	Previous policy			Current policy	P*
	Era 1 (n=100)	Era 2 (n=58)	Total (n=158)	Era 3 (n=15)
	1.2005–12.2014	1.2015–3.2021	1.2005–3.2021	4.2021–1.2024
High-risk patient	41 (41.0%)	17 (29.3%)	58 (36.7%)	8 (53.3%)	0.205
Early allograft dysfunction	54 (54.0%)	8 (13.8%)	62 (39.2%)	2 (13.3%)	0.047
Small-for-size syndrome	41 (41.0%)	16 (27.6%)	57 (36.1%)	3 (20.0%)	0.211
Hepatic artery thrombosis	4 (4.0%)	2 (3.5%)	6 (3.8%)	0 (0%)	1.000
Portal vein thrombosis	10 (10.0%)	8 (13.8%)	18 (11.4%)	3 (20.0%)	0.399
Biliary complications	21 (21.0%)	5 (8.6%)	26 (16.5%)	2 (13.3%)	1.000
90-Day mortality	15 (15.0%)	4 (6.9%)	19 (17.4%)	0 (0%)	0.378
^* Previous policy vs current policy.

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