29 July 2025 : Original article
Steroid Use in ABO-Incompatible Kidney Transplants: Withdrawal vs Maintenance
Dong Hui Shin
BCDEF 1, Ji Teak Kim DE 2, Sung Hwa Kim C 3, Keunryeol Park B 1, Deok Gie Kim ABCE 4*, Jun Young Lee ABCDEFG 1
DOI: 10.12659/AOT.947747
Ann Transplant 2025; 30:e947747
Table 1 Baseline characteristics.
| Variable | Steroid maintenance (n=13) | Steroid withdrawal (n=20) | P value |
|---|---|---|---|
| Age (years) | 46.9±15.8 | 49.9±10.0 | 0.519 |
| Sex, male | 9 (69.2) | 9 (45.0) | 0.172 |
| BMI (kg/m) | 24.8±5.1 | 23.5±2.8 | 0.363 |
| Year of KT | 0.900 | ||
| 2014–2017 | 3 (23.1) | 5 (25.0) | |
| 2018–2021 | 10 (76.9) | 15 (75.0) | |
| Re-transplantation | 0 (0.0) | 1 (5.0) | 0.413 |
| Cause of ESKD | 0.867 | ||
| DM | 5 (38.5) | 8 (40.0) | |
| Hypertension | 1 (7.7) | 3 (15.0) | |
| Glomerular disease | 5 (38.5) | 5 (25.0) | |
| PCKD | 1 (7.7) | 1 (5.0) | |
| Unknown | 1 (7.7) | 3 (15.0) | |
| Dialysis duration (months) | 7.7±12.3 | 15.8±27.6 | 0.333 |
| DM | 5 (38.5) | 10 (50.0) | 0.515 |
| CVD | 0 (0.0) | 1 (5.0) | 0.413 |
| Donor type | 0.297 | ||
| Parent | 3 (23.1) | 3 (15.0) | |
| Offspring | 3 (23.1) | 5 (25.0) | |
| Sibling | 0 (0.0) | 2 (10.0) | |
| Spouse | 5 (38.5) | 10 (50.0) | |
| Other unrelated | 2 (15.4) | 0 (0.0) | |
| Donor age (years) | 48.6±13.2 | 47.7±14.4 | 0.855 |
| Donor sex, male | 9 (69.2) | 11 (55.0) | 0.414 |
| Donor BMI (kg/m) | 26.7±4.4 | 25.6±2.9 | 0.364 |
| Donor creatinine at donation (mg/dL) | 0.98±0.30 | 0.86±0.15 | 0.116 |
| Donor HTN | 2 (15.4) | 7 (35.0) | 0.216 |
| Donor DM | 1 (7.7) | 1 (5.0) | 0.751 |
| CIT (min) | 72.1±18.4 | 76.4±19.0 | 0.522 |
| HLA mismatch | 4.0±1.2 | 3.9±1.2 | 0.753 |
| Induction agent | 0.353 | ||
| IL-2 receptor antibody | 8 (61.5) | 9 (45.0) | |
| Anti-thymocyte globulin | 5 (38.5) | 11 (55.0) | |
| Prescription of valganciclovir at discharge | 8 (61.5) | 7 (35.0) | 0.169 |
| Data are expressed as mean±standard deviation or number (%). BMI – body mass index; CIT – cold ischemic time; CVD – cardiovascular disease; DM – diabetes mellitus; ESKD – end-stage kidney disease; HLA – human leukocyte antigens; HTN – hypertension; KT – kidney transplant; PCKD – polycystic kidney disease. | |||