Steroid Use in ABO-Incompatible Kidney Transplants: Withdrawal vs Maintenance

29 July 2025 : Original article

Dong Hui Shin

^{BCDEF 1}, Ji Teak Kim^{DE 2}, Sung Hwa Kim^{C 3}, Keunryeol Park

^{B 1}, Deok Gie Kim

^{ABCE 4*}, Jun Young Lee

^{ABCDEFG 1}

DOI: 10.12659/AOT.947747

Ann Transplant 2025; 30:e947747

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Table 3 Baseline characteristics.

Variable	Delayed steroid withdrawal (n=14)	Rapid steroid withdrawal (n=6)	P value
Age (years)	50.6±8.6	48.2±13.5	0.636
Sex, male	7 (50.0)	2 (33.3)	0.492
BMI (kg/m)	24.1±2.4	22.1±3.5	0.154
Year of KT			0.091
2014–2017	5 (35.7)	0 (0.0)
2018–2021	9 (64.3)	6 (100)
Re-transplantation	1 (7.1)	0 (0.0)	0.502
Cause of ESKD			0.609
DM	6 (42.9)	2 (33.3)
Hypertension	2 (14.3)	1 (16.7)
Glomerular disease	4 (28.6)	1 (16.7)
PCKD	0 (0.0)	1 (16.7)
Unknown	2 (14.3)	1 (16.7)
Dialysis duration (months)	9.6±11.3	30.8±46.7	0.113
DM	8 (57.1)	2 (33.3)	0.329
CVD	1 (7.1)	0 (0.0)	0.502
Donor type			0.389
Parent	1 (7.1)	2 (33.3)
Offspring	4 (28.6)	1 (16.7)
Sibling	1 (7.1)	1 (16.7)
Spouse	8 (57.1)	2 (28.6)
Other unrelated	0 (0.0)	0 (0.0)
Donor age (years)	45.2±14.7	53.5±12.9	0.249
Donor sex, male	6 (42.9)	5 (83.3)	0.095
Donor BMI (kg/m)	25.3±3.0	26.2±3.0	0.546
Donor creatinine at donation (mg/dL)	0.84±0.12	0.90±0.21	0.405
Donor HTN	5 (35.7)	2 (33.3)	0.919
Donor DM	0 (0.0)	1 (16.7)	0.117
CIT (min)	77.7±20.7	73.3±15.4	0.649
HLA mismatch	4.1±1.5	3.3±0.8	0.287
Induction agent			0.001
IL-2 receptor antibody	3 (21.4)	6 (100)
Anti-thymocyte globulin	11 (78.6)	0 (0.0)
Prescription of valganciclovir at discharge	7 (50.0)	0 (0.0)	0.032
Data are expressed as mean±standard deviation or number (%). BMI – body mass index; CIT – cold ischemic time; CVD – cardiovascular disease; DM – diabetes mellitus; ESKD – end-stage kidney disease; HLA – human leukocyte antigens; HTN – hypertension; KT – kidney transplant; PCKD – polycystic kidney disease.

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