02 September 2025 : Original article
New-Onset Diabetes After Liver Transplantation: An SRTR Database Study of Incidence and Risk Factors
Saxiao Tang AEF 1,2, Shengmin Mei BCD 1, Shichao Shen
BCF 2, Li Wang BCF 2, Yue Wu CDF 2, Jie Xiang ACF 1,2, Zhiwei Li ACDG 1,2*
DOI: 10.12659/AOT.949062
Ann Transplant 2025; 30:e949062
Table 5 Cause of graft failure and patient death comparison between NODAT and non-NODAT.
| Graft failure (%) | NODAT (n=459) | Non-NODAT (n=4913) | P | Patient death (%) | NODAT (n=407) | Non-NODAT (n=3559) | P |
|---|---|---|---|---|---|---|---|
| Primary non-function | 24 (5.2) | 405 (8.2) | 0.024 | Primary graft failure | 23 (5.7) | 282 (7.9) | 0.116 |
| Recurrent primary disease | 32 (7.0) | 326 (6.6) | 0.769 | Cardiovascular/cerebrovascular disease | 47 (11.5) | 412 (11.6) | 1.000 |
| Rejection | 21 (4.6) | 227 (4.6) | 1.000 | Organ failure | 64 (15.7) | 493 (13.9) | 0.293 |
| Infection | 58 (12.6) | 539 (11.0) | 0.277 | Infection | 47 (11.5) | 358 (10.1) | 0.342 |
| Vascular thrombosis | 48 (10.5) | 377 (7.7) | 0.038 | Malignancy | 76 (18.7) | 793 (22.3) | 0.100 |
| Cholangiopathy | 24 (5.2) | 259 (5.3) | 1.000 | Others | 150 (36.9) | 1221 (34.3) | 0.322 |
| Death with graft still functioning | 200 (43.6) | 1803 (36.7) | 0.004 | ||||
| Others | 52 (11.3) | 977 (19.9) | <0.001 | ||||
| NODAT – new-onset diabetes after transplantation. | |||||||