04 November 2025 : Original article
Risk Factors for Development of Post-Transplant Diabetes Mellitus After Kidney Transplantation and Comparison Between Older and Younger Recipients in the Early Post-Transplantation Period: A Single-Center Study
Aleksandra Maria Barbachowska-Kubik ABCDEF 1, Jolanta Gozdowska
AE 1*, Maciej Kosieradzki EF 2, Magdalena Durlik EF 1
DOI: 10.12659/AOT.949855
Ann Transplant 2025; 30:e949855
Table 2 Outcome of logistic regression analysis for PTDM.
| Variable | Univariate models | Multivariate model | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p | OR | 95% CI | p | |
| Sex, Female (vs male) | 1.50 | 0.81–2.78 | 0.198 | – | – | – |
| Age, years | 1.07 | 1.04–1.10 | <0.001 | 1.08 | 1.04–1.11 | <0.001 |
| Age ≥60 years (vs <60 years) | 5.24 | 2.60–10.68 | <0.001 | – | – | – |
| Thymoglobulin | 0.64 | 0.32–1.24 | 0.200 | – | – | – |
| Basiliximab | 1.25 | 0.46–3.09 | 0.638 | – | – | – |
| Methylprednisolone pulses | 2.04 | 0.84–4.76 | 0.103 | – | – | – |
| BMI, kg/m | 1.15 | 1.07–1.25 | <0.001 | 1.12 | 1.02–1.23 | 0.026 |
| Triglycerides, mg/dl | 1.01 | 1.00–1.01 | <0.001 | 1.00 | 1.00–1.01 | 0.046 |
| Hypertriglyceridemia | 6.86 | 2.63–23.51 | <0.001 | 3.54 | 1.12–13.93 | 0.045 |
| Cholesterol, mg/dl | 1.01 | 1.00–1.02 | <0.001 | 1.01 | 1.00–1.01 | 0.111 |
| Hypercholesterolaemia | 2.76 | 1.34–6.16 | 0.008 | – | – | – |
| Mean tacrolimus level | 1.01 | 0.86–1.19 | 0.884 | – | – | – |
| Uric acid, mg/dl | 1.17 | 0.98–1.41 | 0.091 | – | – | – |
| Hyperuricemia | 1.19 | 0.64–2.25 | 0.589 | – | – | – |
| Mean magnesium levels mg/dl | 0.10 | 0.03–0.32 | <0.001 | 0.12 | 0.03–0.46 | 0.003 |
| Hypomagnesemia | 2.34 | 1.19–4.57 | 0.013 | – | – | – |
| BPAR | 2.04 | 0.84–4.76 | 0.103 | – | – | – |
| MI – body mass index; BPAR – biopsy-proven acute rejection; CI – confidence interval; DDKT – deceased donor kidney transplantation; LDKT – living donor kidney transplantation; OR – odds ratio. | ||||||