04 November 2025 : Original article
Risk Factors for Development of Post-Transplant Diabetes Mellitus After Kidney Transplantation and Comparison Between Older and Younger Recipients in the Early Post-Transplantation Period: A Single-Center Study
Aleksandra Maria Barbachowska-Kubik ABCDEF 1, Jolanta Gozdowska
AE 1*, Maciej Kosieradzki EF 2, Magdalena Durlik EF 1
DOI: 10.12659/AOT.949855
Ann Transplant 2025; 30:e949855
Table 4 Comparison of patients aged ≥60 years vs patients aged <60 years with PTDM.
| Variable | Patients with PTDM aged ≥60 years | Patients with PTDM aged <60 years | MD (95% CI) | p |
|---|---|---|---|---|
| N | 24 (100.0) | 31 (100.0) | – | – |
| Thymoglobulin, n (%) | 4 (16.7) | 11 (35.5) | – | 0.212 |
| Basiliximab, n (%) | 3 (12.5) | 4 (12.9) | – | >0.9993 |
| GKS, n (%) | 5 (20.8) | 5 (16.1) | – | 0.7333 |
| Insulin-based therapy, n (%) | 6 (25.0) | 9 (29.0) | – | 0.978 |
| Antidiabetic drugs, n (%) | 19 (79.2) | 24 (77.4) | – | >0.999 |
| Infection within 6 months, n (%) | 16 (66.7) | 14 (45.2) | – | 0.188 |
| Triglycerides, mg/dl, median (IQR) | 188.00 (151.25; 238.50) | 245.00 (152.50; 339.00) | −57.00 (−111.00; 17.00) | 0.1692 |
| Cholesterol, mg/dl, mean±SD | 219.83±51.50 | 199.97±55.82 | 19.87 (−9.58; 49.31) | 0.1821 |
| Creatinine mg/dl, median (IQR) | 1.60 (1.40; 2.02) | 1.45 (1.00; 1.85) | 0.15 (−0.10; 0.60) | 0.1372 |
| BPAR, n (%) | 5 (20.8) | 5 (16.1) | – | 0.7333 |
| CMV, n (%) | 4 (16.7) | 4 (12.9) | – | 0.7183 |
| BKV, n (%) | 2 (8.3) | 6 (19.4) | – | 0.4433 |
| BKV – polyomavirus replication; BPAR – biopsy-proven acute rejection; CI – confidence interval; CMV – cytomegalovirus replication; GKS – additional methylprednisolone pulses; IQR – interquartile range; MD – mean or median difference (≥60 years vs 1 Groups were compared with the test, 2 Mann-Whitney U test, 3 Pearson’s chi-square test, or Fisher’s exact test, as appropriate. | ||||