11 November 2025 : Original article
Invasive Coronary Physiology Assessment for Detecting Microcirculatory Dysfunction in Heart Transplant Recipients
Mateusz Sokolski
ABCDEFG 1,2*, Natalia Oliwia Bernacka CDEF 3, Wiktoria Zychla CDEF 3, Magdalena J. Cielecka BE 1,2, Mateusz Rakowski BE 2,4, Maciej Bochenek BE 1,2, Wiktor Kuliczkowski BE 2,5, Roman Przybylski BEG 2,6, Michał Zakliczyński ABEG 1,2
DOI: 10.12659/AOT.950138
Ann Transplant 2025; 30:e950138
Table 2 Data on heart transplantation in groups of patients with normal and abnormal microcirculation.
| Parameter | Coronary microvascular dysfunction | Normal coronary microcirculation | All (n=33) | P |
|---|---|---|---|---|
| Transport/ischemia characteristics | ||||
| Cardiac arrest time | 1 (13%) | 4 (16%) | 5 (15%) | 0.810 |
| Cold ischemia time (min) | 171.33 (93) | 133.95 (56) | 133.95 (56) | 0.328 |
| Perfusion time (min) | 203.50 [119–226] | 142.50 [107–208] | 142.50 [107–208] | 0.433 |
| Transplantation details | ||||
| Sex mismatch | 4 (50%) | 5 (21%) | 9 (28%) | 0.112 |
| CMV mismatch | 1 (13%) | 5 (21%) | 6 (19%) | 0.601 |
| Recipient blood type | 0, 1 (13%); | 0, 3 (12%); | 0, 4 (12%); | 0.403 |
| A, 4 (50%); | A, 13 (52%); | A, 17 (52%); | ||
| B, 3 (38%); | B, 4 (16%); | B, 7 (21%); | ||
| AB, 0 | AB, 5 (20%) | AB, 5 (15%) | ||
| Transplantation mode (0: urgent, 1: elective) | 4 (50%) | 13 (52%) | 17 (52%) | 0.923 |
| CMV after transplantation | 2 (25%) | 4 (16%) | 6 (18%) | 0.566 |
| Graft rejection incidents in medical history | 1 (13%) | 6 (24%) | 7 (21%) | 0.489 |
| Pacemaker (PM) after transplantation | 3 (38%) | 1 (4%) | 4 (12%) | 0.012 |
| Coronary artery changes according to CAV | 5 (63%) | 9 (36%) | 14 (42%) | 0.186 |
| Categorical variables are presented as numbers with (%). Continuous variables with a normal distribution are shown as mean (SD). Nonparametric variables are presented as the median with upper and lower quartile. CMV – cytomegalovirus; CAV – cardiac allograft vasculopathy. | ||||