09 December 2025 : Original article
Incomplete Immune Tolerance in Pediatric ABO-Incompatible Liver Transplantation: Insights From Donor-Specific Antibody Titers
Wei Qu ABCDEFG 1, Ying Liu ACDEF 2, Ru-Zhou Cai ABCDEF 1, Zhi-Jun Zhu ACDEFG 1*, Li-Ying Sun ACDE 2, Lin Wei ACDE 1, Zhi-Gui Zeng ABCDF 1DOI: 10.12659/AOT.950428
Ann Transplant 2025; 30:e950428
Table 1 Demographic characteristics of pediatric ABOi-LDLT recipients.
| Patient | Sex | Age (months) | Body weight (kg) | Indication for LT | Donor blood group | Graft | Follow-up (months) |
|---|---|---|---|---|---|---|---|
| 1 | M | 5 | 7.8 | BA | A | LLS | 10.6 |
| 2 | M | 109 | 30 | ALF | B | RL (without MHV) | 10.9 |
| 3 | M | 3 | 5.9 | BA | B | LLS | 14.6 |
| 4 | M | 6 | 6.1 | BA | B | LLS | 17.3 |
| 5 | M | 98 | 20 | BA | A | LL (with MHV) | 17.6 |
| 6 | F | 23 | 10 | BA | B | LLS | 17.7 |
| 7 | M | 11 | 9.5 | BA | A | LLS | 20.1 |
| 8 | F | 103 | 25 | BA | B | LL (with MHV) | 21.1 |
| 9 | F | 10 | 9 | BA | B | LLS | 22.9 |
| 10 | M | 22 | 13 | MMA | B | LLS | 23.6 |
| 11 | M | 114 | 15 | Alagille syndrome | B | LLS | 30.7 |
| 12 | F | 11 | 5.5 | Alagille syndrome | A | LLS | 31.8 |
| 13 | F | 7 | 8.1 | BA | A | LLS | 34.1 |
| 14 | F | 8 | 7 | BA | B | LLS | 36.0 |
| 15 | M | 5 | 5.5 | BA | B | LLS | 41.9 |
| 16 | M | 6 | 6.5 | Wilson’s disease | B | LLS | 43.3 |
| 17 | M | 5 | 5 | BA | A | LLS | 43.8 |
| 18 | F | 14 | 9 | BA | B | LLS | 47.2 |
| 19 | M | 10 | 6.9 | BA | A | LLS | 47.4 |
| 20 | F | 10 | 7 | BA | A | LLS | 49.5 |
| 21 | M | 14 | 9.5 | BA | A | LLS | 50.9 |
| 22 | F | 6 | 7.4 | IPH | A | LLS | 52.4 |
| 23 | F | 4 | 8 | BA | B | LLS | 53.2 |
| 24 | M | 5 | 8.5 | BA | B | LLS | 54.4 |
| 25 | M | 9 | 7.5 | BA | B | LLS | 56.3 |
| 26 | F | 13 | 8 | BA | B | LLS | 56.6 |
| 27 | F | 14 | 8 | BA | B | LLS | 57.3 |
| 28 | F | 6 | 5.7 | BA | B | LLS | 63.0 |
| 29 | M | 8 | 7.5 | BA | B | LLS | 95.7 |
| ABOi-LDLT – ABO-incompatible living donor liver transplantation; ALF – acute liver failure; BA – biliary atresia; F – Female; IPH – idiopathic portal hypertension; LL – left lobe; LLS – left lateral segment; LT – liver transplantation; M – Male; MHV – middle hepatic vein; MMA – methylmalonic acidemia; RL – right lobe. | |||||||