18 November 2025 : Original article
G-CSF Priming of Haploidentical Bone Marrow: Effects on Cell Yield, Collection Efficiency, and Tolerogenic Graft Composition
Nadira Duraković
ACDEFG 1,2*, Antonija Babić BCDE 3, Lana Desnica BD 1, Zinaida Perić BD 4,5, Ranka Serventi Seiwerth B 1, Drago Batinić ADE 2, Radovan Vrhovac AD 1,2
DOI: 10.12659/AOT.950586
Ann Transplant 2025; 30:e950586
Table 2 Graft characteristics and engraftment outcomes.
| Characteristics | |
|---|---|
| Number of infused cells (median, range)/kg BW | |
| TNCs | 5.04×10 (1.76–12.93) |
| CD34 | 1.65×10 (0.28–4.47) |
| Engraftment outcomes, n (%) | |
| Achieved | 56 (92) |
| Primary rejection | 2 (3) |
| Secondary rejection* | 2 (3) |
| Death in aplasia | 3 (5) |
| Time to recovery (median, range) | |
| ANC >0.5×10/L | 23 (12–38) |
| PLT >20×10/L | 33 (15–81) |
| ANC – absolute neutrophil count; BW – body weight; PLT – platelet count; TNCs – total nucleated cells. * Engraftment was initially achieved in these patients; thus, the total percentage of engraftment outcomes exceeds 100%. | |