28 July 2020>: Original Paper
Effect of Concentration/Dose Ratio in Kidney Transplant Recipients Receiving LCP-Tacrolimus or Immediate-Release Tacrolimus: Post Hoc Analysis of a Phase 3 Clinical Trial
Barbara Suwelack 1ABDE* , Suphamai Bunnapradist 2BDE , Ulf Meier-Kriesche 3ACDE , Daniel R. Stevens 3ACDE , Claudio Procaccianti 4ACDE , Roberto Morganti 4ACDE , Klemens Budde 5ACDEDOI: 10.12659/AOT.923278
Ann Transplant 2020; 25:e923278
Figure 1 Patient disposition. This post hoc analysis included patients who had a calculable day 30 C/D ratio based on central or local laboratory data. Trough attainment on days 2–5 after treatment, clinical outcomes, and eGFR were analyzed in all patients included in the post hoc analysis. Average trough concentration and total daily dose were determined in patients whose C/D ratios were calculated from central laboratory data only. C/D – concentration/dose; IR-Tac – immediate-release tacrolimus; LCPT – LCP-tacrolimus.