28 July 2020 : Original article
Effect of Concentration/Dose Ratio in De Novo Kidney Transplant Recipients Receiving LCP-Tacrolimus or Immediate-Release Tacrolimus: Post Hoc Analysis of a Phase 3 Clinical Trial
Barbara Suwelack1ABDE*, Suphamai Bunnapradist2BDE, Ulf Meier-Kriesche3ACDE, Daniel R. Stevens3ACDE, Claudio Procaccianti4ACDE, Roberto Morganti4ACDE, Klemens Budde5ACDEDOI: 10.12659/AOT.923278
Ann Transplant 2020; 25:e923278

Figure 1 Patient disposition. This post hoc analysis included patients who had a calculable day 30 C/D ratio based on central or local laboratory data. Trough attainment on days 2–5 after treatment, clinical outcomes, and eGFR were analyzed in all patients included in the post hoc analysis. Average trough concentration and total daily dose were determined in patients whose C/D ratios were calculated from central laboratory data only. C/D – concentration/dose; IR-Tac – immediate-release tacrolimus; LCPT – LCP-tacrolimus.