28 July 2020 : Original article
Effect of Concentration/Dose Ratio in De Novo Kidney Transplant Recipients Receiving LCP-Tacrolimus or Immediate-Release Tacrolimus: Post Hoc Analysis of a Phase 3 Clinical Trial
Barbara Suwelack1ABDE*, Suphamai Bunnapradist2BDE, Ulf Meier-Kriesche3ACDE, Daniel R. Stevens3ACDE, Claudio Procaccianti4ACDE, Roberto Morganti4ACDE, Klemens Budde5ACDEDOI: 10.12659/AOT.923278
Ann Transplant 2020; 25:e923278

Figure 5 Total daily dose (A) and trough concentrations (B) of tacrolimus in slow metabolizers. The analysis population consisted of patients who had a calculable day 30 C/D ratio based on central laboratory data only. Central boxes indicate the 25th to 75th percentile, and central lines the median (50th percentile). Whiskers indicate full concentration ranges. Lines connect the mean trough concentrations. C/D – concentration/dose; IR-Tac – immediate-release tacrolimus; LCPT – LCP-tacrolimus.