Suppression of Allograft Fibrosis by Regulation of Mammalian Target of Rapamycin-Related Protein Expression in Kidney-Transplanted Recipients Treated with Everolimus and Reduced Tacrolimus

Shun Nishioka; Takeshi Ishimura; Takahito Endo; Naoki Yokoyama; Satoshi Ogawa; Masato Fujisawa

doi:10.12659/AOT.926476

12 January 2021: Original Paper

Suppression of Allograft Fibrosis by Regulation of Mammalian Target of Rapamycin-Related Protein Expression in Kidney-Transplanted Recipients Treated with Everolimus and Reduced Tacrolimus

Shun Nishioka ^ABCDE , Takeshi Ishimura ^ACDE* , Takahito Endo ^B , Naoki Yokoyama ^BC , Satoshi Ogawa ^BCD , Masato Fujisawa ^E

DOI: 10.12659/AOT.926476

Ann Transplant 2021; 26:e926476

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Figure 1 Flow chart of the patient selection process. KTx – kidney transplantation; Tac – tacrolimus; CNI – calcineurin inhibitor; eGFR – estimated-glomerular filtration rate (ml/min/1.73 m2); AR – acute rejection; EVR – everolimus.

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Suppression of Allograft Fibrosis by Regulation of Mammalian Target of Rapamycin-Related Protein Expression in Kidney-Transplanted Recipients Treated with Everolimus and Reduced Tacrolimus

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