Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

01 December 2021 : Original article  

Solid-Phase C1q/C3d Fixing Readouts Correlate with High Median Fluorescence Intensity (MFI) De Novo Donor-Specific HLA Antibodies and C4d⁺ Antibody-Mediated Rejection in Kidney Transplant Recipients

Vasishta S. Tatapudi1BDEF, Dessislava Kopchaliiska2ABC, Gilberto J. da Gente2C, Owen F. Buenaventura2BC, Manpreet Singh3BC, Zoltan Laszik4BC, Deborah B. Adey1CDE, Raja Rajalingam ORCID logo2ADEF*

DOI: 10.12659/AOT.934175

Ann Transplant 2021; 26:e934175

Figure 3 Nature of de novo donor-specific HLA class II antibodies in kidney transplant recipientsMost de novo DSA in kidney transplant recipients are HLA-DQ antigen-specific. Shown is the relationship between median fluorescence intensity (MFI) of de novo class II IgG DSA and the ability of C1q or C3d-binding capacity.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358