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05 July 2022: Original Paper

Cardiac and Pulmonary Histopathology in Baboons Following Genetically-Engineered Pig Orthotopic Heart Transplantation

Silvio H. Litovsky 1BDE , Jeremy B. Foote 2BCDE , Abhijit Jagdale 3BE , Gregory Walcott 4BE , Hayato Iwase 3BDE , Mohamed H. Bikhet 3BDE , Takayuki Yamamoto 3BE , Christophe Hansen-Estruch 3BE , Mohamed B. Ezzelarab 5BE , David Ayares 6AE , Waldemar F. Carlo 7BE , Leslie A. Rhodes 7BE , Jack H. Crawford 8BE , Santiago Borasino 8BE , Robert J. Dabal 8BE , Luz A. Padilla 8BE , Hidetaka Hara 3BE , David K.C. Cooper 3ABDEFG* , David C. Cleveland 8ABDEFG

DOI: 10.12659/AOT.935338

Ann Transplant 2022; 27:e935338

Figure 1 Elevations in pro-inflammatory cytokines after pig OHTx in baboons (n=4)(A) IL-1β, (B) IL-6, (C) IL-8, (D) TNFα were measured at different time-points by Luminex multianalyte ELISA.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358