05 July 2022 : Original article
Cardiac and Pulmonary Histopathology in Baboons Following Genetically-Engineered Pig Orthotopic Heart Transplantation
Silvio H. Litovsky1BDE, Jeremy B. Foote2BCDE, Abhijit Jagdale3BE, Gregory Walcott4BE, Hayato Iwase3BDE, Mohamed H. Bikhet3BDE, Takayuki Yamamoto3BE, Christophe Hansen-Estruch3BE, Mohamed B. Ezzelarab5BE, David Ayares6AE, Waldemar F. Carlo7BE, Leslie A. Rhodes7BE, Jack H. Crawford8BE, Santiago Borasino8BE, Robert J. Dabal8BE, Luz A. Padilla8BE, Hidetaka Hara3BE, David K.C. Cooper3ABDEFG*, David C. Cleveland8ABDEFGDOI: 10.12659/AOT.935338
Ann Transplant 2022; 27:e935338
Figure 3 Histopathology of the baboon lungs (A–D) in B37367 at necropsyThe lungs showed diffuse prominent airway inflammation (A) that included the airway epithelium (B). The infiltrate contained a high number of eosinophils. The arteries were also inflamed, as was the perivascular tissue (C). Eosinophils were seen in the perivascular tissue and vascular media (D).