29 March 2022 : Original article
Bioinformatics Identification of Candidate Biomarkers in Endomyocardial Biopsy and Peripheral Blood for Cardiac Allograft Rejection
Kang Luo1ABCDEFG, Lin Li2BCDE, Mingyao Meng2DEFG, Yan Chen1BC, Zongliu Hou2EFDOI: 10.12659/AOT.935488
Ann Transplant 2022; 27:e935488
Figure 1 Differential expression of genes from endomyocardial biopsy and peripheral blood samples(A) Volcano plot of 57 502 genes expressed differentially in endomyocardial biopsy of patients with and without cardiac rejection. (B) Volcano plot of 131 624 genes expressed differentially in peripheral blood of patients with and without cardiac rejection. Red plots represent significantly upregulated genes (logFC ≥1, P value <0.05), blue plots are significantly downregulated genes (logFC ≤−1, P value <0.05), while the gray ones demonstrate genes with non-differential expression. Volcano plot graphs were created using the OmicStudio tools available at https://www.omicstudio.cn/tool.