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29 March 2022: Database Analysis

Bioinformatics Identification of Candidate Biomarkers in Endomyocardial Biopsy and Peripheral Blood for Cardiac Allograft Rejection

Kang Luo 1ABCDEFG , Lin Li 2BCDE , Mingyao Meng 2DEFG , Yan Chen 1BC , Zongliu Hou 2EF

DOI: 10.12659/AOT.935488

Ann Transplant 2022; 27:e935488

Figure 1 Differential expression of genes from endomyocardial biopsy and peripheral blood samples(A) Volcano plot of 57 502 genes expressed differentially in endomyocardial biopsy of patients with and without cardiac rejection. (B) Volcano plot of 131 624 genes expressed differentially in peripheral blood of patients with and without cardiac rejection. Red plots represent significantly upregulated genes (logFC ≥1, P value <0.05), blue plots are significantly downregulated genes (logFC ≤−1, P value <0.05), while the gray ones demonstrate genes with non-differential expression. Volcano plot graphs were created using the OmicStudio tools available at https://www.omicstudio.cn/tool.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358