30 January 2024>: Original Paper
Cyclosporine A Does Not Mitigate Liver Ischemia/Reperfusion Injury in an Ex Vivo Porcine Model of Donation After Circulatory Death
Joshua Hefler 1ABCDEF , Sanaz Hatami 23ABCDE , Aducio Thiesen 4DE , Mitchell J. Wagner 1BE , Guilherme Mainardi 1BE , Sayed Himmat 1BE , Constantine J. Karvellas 2AE , David L. Bigam 1AE , Darren H. Freed 13AEG , A.M. James Shapiro 135ADEG*DOI: 10.12659/AOT.941054
Ann Transplant 2024; 29:e941054
Figure 3 Perfusion parameters for control (Ctrl) and treated (CsA) livers subject to 45 or 60 minutes of warm ischemia (45 m WIT, 60 m WIT) and 2 or 4 hours of cold ischemia (2 h CIT, 4 h CIT). Created in Prism (v17.0, GraphPad Software Inc.). HAP – hepatic artery pressure; HAF – hepatic artery flow; HAR – hepatic artery resistance; PVP – portal venous pressure; PVF – portal venous flow; PVR – portal venous resistance.