Does Antibiotic Use Increase the Risk of Post-Transplantation Diabetes Mellitus? A Retrospective Study of Renal Transplant Patients

Zhenwei Jiang; Caomei Xu; Huan Hou; Xuping Yang; Minyan Qian; Lian Zuo; Peipei Wang; Qing Qian; Yan Jiang; Nan Hu

doi:10.12659/AOT.943282

30 April 2024 : Original article

Does Antibiotic Use Increase the Risk of Post-Transplantation Diabetes Mellitus? A Retrospective Study of Renal Transplant Patients

Zhenwei Jiang^1BCDEF, Caomei Xu^1CE, Huan Hou^2C, Xuping Yang^1D, Minyan Qian^1B, Lian Zuo^1B, Peipei Wang^3B, Qing Qian^1D, Yan Jiang^1B, Nan Hu^1AG*

DOI: 10.12659/AOT.943282

Ann Transplant 2024; 29:e943282

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Figure 2 Influence of CYP3A5*3 polymorphism on TAC C0 and C0/DTAC C0: TAC trough level; TAC C0/D: TAC dose-adjusted trough level. (A, B) TAC C0 and C0/D over time by CYP3A5*3 genotype. genotype wild-type vs mutant homozygous genotype *: * P<0.05, ** P<0.01, *** P<0.001; wild-type vs mutant heterozygous genotype#: # P<0.05, ## P<0.01, ### P<0.001; mutant heterozygous genotype vs mutant homozygous genotype$: $ P<0.05, $$ P<0.01, $$$ P<0.001. Values are expressed as the mean±standard deviation. The data were analyzed by one-way ANOVA, with post hoc Bonferroni’s or Games-Howell’s multiple comparison tests based on homogeneity of variance.

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Does Antibiotic Use Increase the Risk of Post-Transplantation Diabetes Mellitus? A Retrospective Study of Renal Transplant Patients

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