Clonal Hematopoiesis-Associated Gene Mutations Affect Acute Graft-Versus-Host Disease After Hematopoietic Stem Cell Transplantation in AML Patients

Xiaoxuan Wei; Sai Huang; Zhenyang Gu; Jing Liu; Meng Li; Xiangshu Jin; Jian Bo; Fei Li; Yu Jing; Xiaoning Gao; Liping Dou; Daihong Liu; Chunji Gao

doi:10.12659/AOT.943688

02 July 2024 : Original article

Clonal Hematopoiesis-Associated Gene Mutations Affect Acute Graft-Versus-Host Disease After Hematopoietic Stem Cell Transplantation in AML Patients

Xiaoxuan Wei^12ABCDEF, Sai Huang^1ABF, Zhenyang Gu^1ADEF, Jing Liu^1ADEF, Meng Li^1AF, Xiangshu Jin^1AF, Jian Bo^1AF, Fei Li^1A, Yu Jing^1A, Xiaoning Gao^1A, Liping Dou^1AB, Daihong Liu^1A, Chunji Gao^1ADEF*

DOI: 10.12659/AOT.943688

Ann Transplant 2024; 29:e943688

Authors information Article notes Copyright and License information

Introduction Material and Methods Results Discussion Conclusions References

Related articles Order reprints Share article Share by email

View HTML version

Figure 4 Kaplan-Meier curves depict the leukemia-free survival. (A, B) For patients undergoing HSCT, TA-TMA, and a poor pretransplant status were associated with a significantly shorter LFS. (C, D) Only TA-TMA was connected to a shorter LFS in patients had haplo-HSCT. HSCT – hematopoietic stem cell transplantation; TA-TMA – transplantation-associated thrombotic microangiopathy; LFS – leukemia-free survival; haplo-HSCT – haploidentical hematopoietic stem cell transplantation; CR – complete remission; PR – partial response; NR – no response. Figure was created using GraphPad Prism 10 by Dotmatics.

Back to the Article

Clonal Hematopoiesis-Associated Gene Mutations Affect Acute Graft-Versus-Host Disease After Hematopoietic Stem Cell Transplantation in AML Patients

Your Privacy