17 July 2020 : Original article
Kidney Transplantation and “Sex Mismatch”: A 10-Year Single-Center Analysis
Karol Graňák1ABCDE, Lea Kováčiková1ABC, Petra Skálová1AB, Matej Vnučák1BDE, Juraj Miklušica1ABCD, Ľudovít Laca1ABC, Marián Mokáň2FG, Ivana Dedinská1ACEF*DOI: 10.12659/AOT.921117
Ann Transplant 2020; 25:e921117
Table 2 Group characteristics – female donor.
| Female donor (n=68) | Male recipient n=49 | Female recipient n=19 | P value |
|---|---|---|---|
| Age of the donor (years) | 49.2±14.1 | 43.2±16.2 | 0.1358 |
| BMI of the donor (kg/m2) | 24.6±3.6 | 24.3±4.8 | 0.7803 |
| ECD donor (%) | 40.8 | 22.4 | 0.1583 |
| eGFR at the time of procurement (ml/min) | 75.5±19.7 | 62.9±21.8 | |
| QVPU before procurement (g/sampling) | 0.43±0.4 | 0.66±0.45 | |
| Age of the recipient (years) | 45.7±12.7 | 48.7±10.7 | 0.3657 |
| CIT (min) | 743±301 | 657±306 | 0.2965 |
| DGF (%)* | 10.2 | 15.8 | 0.5232 |
| BMI of the recipient (kg/m2) | 25.4±3.5 | 25.2±3.5 | 0.8332 |
| Induction: basiliximab/daclizumab (%) | 51 | 42.1 | 0.5131 |
| Induction: thymoglobulin (%) | 26.5 | 36.8 | 0.4062 |
| Induction: None (%) | 22.5 | 21.1 | 0.9014 |
| Tacrolimus (%) | 86.7 | 84.2 | 0.7913 |
| PRA (%) | 2.9±1.3 | 3.3±2.1 | 0.3460 |
| Mismatch A | 1.1±0.7 | 1.2±0.6 | 0.5850 |
| Mismatch B | 1.2±0.7 | 1.3±0.6 | 0.5850 |
| Mismatch DR | 0.7±0.6 | 0.9.±0.6 | 0.2218 |
| Creatinine D7 (μmol/l) | 267±233.3 | 243±211 | 0.6975 |
| Creatinine M1 (μmol/l) | 174±76 | 142±45 | 0.0906 |
| Creatinine M3 (μmol/l) | 179±45 | 144±46 | |
| Creatinine M6 (μmol/l) | 174±48 | 145±48 | |
| Creatinine Y1 (μmol/l) | 172±61 | 128±40 | |
| Creatinine Y3 (μmol/l) | 155±4.7 | 116±44 | |
| Creatinine Y5 (μmol/l) | 143±32 | 127±50 | 0.1218 |
| eGFR M1 (ml/min) | 42.5±13.2 | 38±9,1 | 0.1776 |
| eGFR M3 (ml/min) | 39.5±9.5 | 37.8±11 | 0.5287 |
| eGFR M6 (ml/min) | 40.7±12.7 | 39.5±12.3 | 0.7255 |
| eGFR R1 (ml/min) | 42.8±13.9 | 43.7±13.1 | 0.8085 |
| eGFR R3 (ml/min) | 46.3±11.4 | 49.4±18 | 0.3994 |
| eGFR R5 (ml/min) | 48.9±12 | 44.1±15.5 | 0.1781 |
| Acute rejection in anamnesis (%)** | 36.7 | 5.3 | |
| KT – kidney transplantation; BMI – body mass index; ECD – expanded criteria donors; eGFR – estimated glomerular filtration rate (according to CKD/EPI formula); QVPU – quantitative proteinuria; CIT – cold ischemia time; DGF – delayed graft function; D – day; M – month; Y – year. * Needed dialysis treatment in the first week after kidney transplantation; ** follow up: 1 year. | |||