08 September 2020 : Original article
Prediction of Liver Prognosis from Pre-Transplant Renal Function Adjusted by Diuretics and Urinary Abnormalities in Adult-to-Adult Living Donor Liver Transplantation
Mineaki Kitamura1ABCDEFG*, Masaaki Hidaka2ABDE, Kumiko Muta1BC, Satoshi Miuma3BDE, Hisamitsu Miyaaki3CD, Mitsuhisa Takatsuki2D, Kazuhiko Nakao3D, Susumu Eguchi2DE, Hiroshi Mukae4D, Tomoya Nishino1ACDEDOI: 10.12659/AOT.924805
Ann Transplant 2020; 25:e924805
Table 3 Multiple linear regression analysis models of eGFR immediately before and one year after transplantation.
| Before transplant | One year after transplant | |||||
|---|---|---|---|---|---|---|
| Sβ | SE | P value | Sβ | SE | P value | |
| Recipient age (year) | −0.409 | 0.20 | <0.001 | −0.492 | 0.15 | <0.001 |
| Recipient sex, if female | −0.021 | 2.28 | 0.77 | 0.003 | 1.73 | 0.97 |
| Recipient body weight (kg) | −0.172 | 0.16 | 0.02 | 0.009 | 0.12 | 0.91 |
| Cirrhosis due to HCV | −0.029 | 2.13 | 0.66 | −0.030 | 1.61 | 0.68 |
| Diabetes | 0.024 | 2.44 | 0.74 | 0.007 | 1.85 | 0.92 |
| Hypertension | −0.047 | 2.80 | 0.39 | −0.004 | 2.12 | 0.95 |
| Diuretics | −0.157 | 2.19 | 0.02 | 0.016 | 1.66 | 0.83 |
| Hemoglobin (g/dL) | 0.337 | 0.98 | <0.001 | 0.205 | 0.74 | 0.009 |
| Albumin (g/dL) | −0.119 | 3.44 | 0.07 | −0.168 | 2.60 | 0.02 |
| Proteinuria >1+ | −0.029 | 3.44 | 0.67 | −0.108 | 2.60 | 0.13 |
| Hematuria >1+ | −0.127 | 2.58 | 0.06 | 0.072 | 1.95 | 0.33 |
| r | 0.39 | 0.29 | ||||
| Sβ – standardized β; SE – standard error; HCV – hepatitis C virus. Multivariate analyses were performed to elucidate the factors associated with renal function before and 1 year after transplantation. Based on clinical importance and availability, the following variables were assessed: recipient age and sex; body weight; hepatitis C virus (HCV) status; use of diuretics; and presence of pretransplant diabetes, presence of hypertension, hemoglobin levels, albumin levels, proteinuria >1+, and hematuria >1+. | ||||||