08 September 2020: Original Paper
Prediction of Liver Prognosis from Pre-Transplant Renal Function Adjusted by Diuretics and Urinary Abnormalities in Adult-to-Adult Living Donor Liver Transplantation
Mineaki Kitamura 1ABCDEFG* , Masaaki Hidaka 2ABDE , Kumiko Muta 1BC , Satoshi Miuma 3BDE , Hisamitsu Miyaaki 3CD , Mitsuhisa Takatsuki 2D , Kazuhiko Nakao 3D , Susumu Eguchi 2DE , Hiroshi Mukae 4D , Tomoya Nishino 1ACDEDOI: 10.12659/AOT.924805
Ann Transplant 2020; 25:e924805
Table 4 Multiple Cox regression analysis of liver transplant prognostic factors.
| Model 1 | Model 2 | Model 3 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | HR | 95% CI | P value | |
| Recipient age, per 10 years | 1.11 | 0.88–1.45 | 0.38 | 1.13 | 0.87–1.49 | 0.37 | 1.14 | 0.88–1.48 | 0.31 |
| Recipient sex, Male Female | 0.98 | 0.60–1.59 | 0.92 | 0.98 | 0.61–1.61 | 0.95 | 0.96 | 0.60–1.56 | 0.87 |
| Donor age, per 10 years | 1.42 | 1.19–1.70 | 1.43 | 1.20–1.71 | 1.46 | 1.21–1.76 | |||
| Diabetes | 1.54 | 0.91–2.58 | 0.11 | 1.50 | 0.88–2.53 | 0.13 | 1.50 | 0.88–2.52 | 0.13 |
| Hypertension | 1.52 | 0.86–2.52 | 0.15 | 1.46 | 0.84–2.48 | 0.17 | 1.50 | 0.84–2.63 | 0.17 |
| Graft volume/standard liver volume per 10% | 0.84 | 0.69–1.02 | 0.08 | 0.85 | 0.70–1.03 | 0.11 | 0.83 | 0.69–1.01 | 0.06 |
| Estimated glomerular filtration rate, per 10 mL/min | 0.90 | 0.82–0.98 | 0.01 | 0.90 | 0.82–0.98 | 0.02 | 0.86 | 0.78–0.95 | 0.003 |
| Hepatitis C virus infection | 1.26 | 0.79–2.02 | 0.33 | ||||||
| Total bilirubin, per 1 mg/dL | 1.00 | 0.98–1.03 | 0.70 | ||||||
| Use of diuretics | 0.57 | 0.35–0.97 | 0.04 | ||||||
| Urinary abnormalities* | 0.90 | 0.49–1.59 | 0.73 | ||||||
| * Hematuria >1+ and/or proteinuria >1. CI – confidence interval; HR – hazard ratio. | |||||||||