04 August 2020 : Original article
Inferior Vena Cava Constriction After Liver Transplantation Is a Severe Complication Requiring Individually Adapted Treatment: Report of a Single-Center Experience
Jan-Paul Gundlach1CDEF*, Rainer Günther2B, Marcus Both3BD, Jens Trentmann3BD, Jost Philipp Schäfer3BCD, Jochen T. Cremer4B, Christoph Röcken5BDE, Thomas Becker1DEG, Felix Braun1ABD, Alexander Bernsmeier1CDEDOI: 10.12659/AOT.925194
Ann Transplant 2020; 25:e925194
Table 1 Literature overview of systematic studies comprising thrombosis and stenosis with respective diagnostic tools and treatment options.
# | Author & year | Time of study (yrs) | Thrombosis vs. stenosis | Number of findings/LT (patients) | Children | Method & time of diagnosis | Treatment & outcome (n) |
---|---|---|---|---|---|---|---|
1 | Cardella JF et al.1986 []12 | t+s | 5/46 | Partly | Angiography (n=18) | PTA (1) | |
2 | Wozney P et al.1986 []2 | 5 | t | 1/625 (477) | n=204 | Angiography (n=104)1 m | Re-LT |
3 | Stiglbauer R et al.1990 []13 | s | 12/159 | Angiography (n=34)45 d | Watch & wait or revision | ||
4 | Raby N et al.1991 []14 | s(+t) | 4/600 | US+angiography8 m – 4.5 yrs | PTA (3), revision (1); 1 died | ||
5 | Brouwers MA et al.1994 []7 | 14 | t+s | 6/245 | US | Revision; thrombectomy transarterial or via cavotomy | |
6 | Kok T et al.1998 []15 | t+s | 9/268 | US + angiography | |||
7 | Settmacher U et al.2000 []8 | 10 | s | 17/1000 | US (add. angiography, CT scan, or MRI)1w – 3.5 yrs | Conservative (1), PTA (3), surgical (4), Denver shunt (3), Re-LT (5); 3 died | |
8 | Buell JF et al.2002 []16 | 12 | s | 12/600 (325) | Yes | US+angiography2 m + 10 yrs | PTA (6) or stenting (4); 2 late recurrence |
9 | Jiang L et al.2002 []17 | s | 6/46 | US + angiography | PTA or stenting | ||
10 | Jia YP et al.2007 []18 | 7 | t | 10/286 | Partly | US5–13 d | Drug therapy |
11 | Yilmaz A et al.2007 []19 | 8 | s | 6/75 | Yes | PTA, stenting; Re-LT | |
12 | Ma Y et al.2008 []20 | 7 | s | 10/776 | US + angiography | PTA (8) or stent, Re-LT (2); 3 died | |
13 | Boraschi C et al.2016 []21 | 4 | t | 1/170 | US + multidetector CT90 d | Drug therapy | |
14 | Galloux A et al.2018 []22 | 24 | s | 26/917 (792) | Yes | Day 1–8.75 yrs | Re-LT (3) |
15 | Gundlach JP et al.2020 | 4 | t+s | 6/138 (125) | US, CT + angiography1 w – 9 m | Interv. thrombectomy, AV-fistula + PTA (1); transartrial thrombectomy (1); PTA (1) or conservative; 3 died | |
Systematic studies (>10 patients) with emphasis on vascular complications. The table gives detailed information on covered years within the studies; number of stenotic (s) or thrombotic (t) findings and pediatric transplantations. In addition, diagnostic options are demonstrated (US – ultrasound; CT – computer tomography; MRI – magnetic resonance imaging), the time of postoperative diagnosis (d – days; m – months; yrs – years) period after LT (time), and an overview of the treatment options. |