06 November 2020 : Original article
Outcomes of Living-Donor Kidney Transplantation in Female Recipients with Possible Pregnancy-Related Pre-Sensitization According to Donor Relationship
Jee Yeon Kim1BCDEF, Mun Chae Choi2BCD, Dong Hyun Kim1BCD, Youngmin Ko1BCD, Seong Jun Lim1B, Joo Hee Jung1B, Hyunwook Kwon1BCD, Young Hoon Kim1ABE, Sung Shin1ABCDEF*, Duck Jong Han1ABEDOI: 10.12659/AOT.925229
Ann Transplant 2020; 25:e925229
Table 2 Cox proportional hazards model analysis of graft survival.
| Univariate | Multivariable | |||||||
|---|---|---|---|---|---|---|---|---|
| Hazard ratio | 95% CI | P value | Hazard ratio | 95% CI | P value | |||
| Group | ||||||||
| Offspring to mother | 1 | 0.690 | 1 | 0.876 | ||||
| Husband to wife | 0.90 | 0.28 | 2.96 | 0.865 | 0.70 | 0.14 | 3.40 | 0.654 |
| Other unrelated | 1.65 | 0.41 | 6.62 | 0.477 | 1.15 | 0.23 | 5.82 | 0.871 |
| Age | 1.06 | 1.00 | 1.13 | 0.069 | 1.06 | 0.99 | 1.13 | 0.099 |
| BMI | 1.13 | 0.98 | 1.30 | 0.086 | 1.14 | 0.97 | 1.34 | 0.110 |
| Number of HLA mismatch (ABDR) | 1.26 | 0.87 | 1.83 | 0.229 | ||||
| Number of HLA mismatch (DR) | 1.96 | 0.78 | 4.91 | 0.151 | 3.18 | 0.90 | 11.25 | 0.072 |
| Pre-transplant DSA | 2.06 | 0.57 | 7.49 | 0.270 | ||||
| ABO-incompatibility | 1.78 | 0.60 | 5.30 | 0.304 | ||||
| Cold ischemic time | 1.01 | 0.99 | 1.03 | 0.350 | ||||
| Donor age | 1.01 | 0.96 | 1.05 | 0.807 | ||||
| Donor creatinine | 3.97 | 0.10 | 162.5 | 0.466 | ||||
| BMI – body mass index; HLA – human leukocyte antigen; DSA – donor-specific antibody; CI – confidence interval. | ||||||||