16 October 2020 : Original article
Expression of 6 Biomarkers in Liver Grafts After Pediatric Liver Transplantation: Correlations with Histology, Biochemistry, and Outcome
Silja H. Voutilainen1BCDEF*, Silja K. Kosola2BE, Jouko Lohi3BE, Aino Mutka3BE, Timo Jahnukainen4BE, Mikko Pakarinen1AEG, Hannu Jalanko4ACDEGDOI: 10.12659/AOT.925980
Ann Transplant 2020; 25:e925980
Table 1 Patient characteristics of all patients (n=51). Data presented as number of patients (percentage) for non-continuous variables and as median (IQR) for continuous parameters.
| All patients (n=51) | |
|---|---|
| 23/28 | |
| Biliary atresia n (%) | 19 (34) |
| Metabolic disease n (%)* | 8 (16) |
| Hepatitis n(%) | 7 (14) |
| Hepatic malignancy n (%) | 5 (10) |
| PKD/congenital fibrosis n (%) | 4 (8) |
| Other n (%)** | 8 (14) |
| Surgical characteristics | |
| 3.3 (1.3–13.6) | |
| 11.3 (4.1–18.0) | |
| 18.2 (10.9–23.2) | |
| ALT (U/L) | 21 (14–32) |
| GT (U/L) | 17 (13–34) |
| Total bilirubin (μmol/L) | 10 (8–14) |
| Prealbumin (mg/L) | 210 (170–238) |
| Platelets (E9/L) | 216 (171–282) |
| 8.4 (7.4–9.3) | |
| 25.7 (19.4–32.3) | |
| ALT – alanine transaminase; AP – alkaline phosphatase; GT – γ-glutamyl transferase; IQR – interquartile range; LT – liver transplantation; PKD – polycystic kidney disease; * Diagnostic group metabolic included: Familial hypercholesterolemia (1), hyperoxaluria (1), morbus Wilson (1), OTC-deficiency (1), and tyrosinemia (4). ** Diagnostic group others included: Budd-Chiari syndrome (1), HUS (1), extrahepatic portal vein thrombosis (1), liver failure of unknown etiology (1), MIRAS mitochondrial recessive ataxia syndrome (1), iron poisoning (2), and sclerosing cholangitis (1). | |