22 June 2021: Original Paper
Shift in Living Kidney Donor Demographics Over the Past 50 Years in a German Transplant Center
Claudia Sommerer 1ACDEF* , Zoi Bougioukou 1BCDEF , Vasileios L. Georgiou 2CD , Arianeb Mehrabi 3E , Martin Zeier 1EDOI: 10.12659/AOT.929693
Ann Transplant 2021; 26:e929693
Table 1 Demographics of living kidney donors from different countries.
| Heidelberg (Germany)2001–2016N=606 | Euro-transplant2011–2016N=8.132(ref. 23) | CRISTAL-donneur (France)2007–2017N=3.877(ref. 13) | Oslo (Norway)1963–2007N=2.268*(ref. 6) | NHSBT data (UK)2006–2017N=11.651(ref. 14) | ANZDATA (Australia)2004–2013N=3.253(ref. 15) | SRTR dataCaucasian (US)2005–2017N=57.992(ref. 12) | |
|---|---|---|---|---|---|---|---|
| Gender, Female, n (%) | 355 (58.6) | 4765 (58.6) | 2415 (62.3) | 1122 (59) | 6217 (53.4) | 1859 (57) | 35871 (61.9) |
| Age, median (IQR) | 50.4 (43.0–58.7) | 16–55: 4862 (59.8)56–64: 2161 (26.6)65+: 1107 (13.6)# | 51 (42–59) | 46.0 (11.5)& | nt | 50 (42–58) | 44 (32–54) |
| High age (years), n (%) | >65: 56 (9.2)>70: 13 (2.1) | >64: 1107 (13.6) | >56: 1190 (30.7) | >70: 89 (3.9) | >60: 2006 (17.2)>70: 272 (2.3) | >65: 252 (7.7) | >50: 18675 (32.2) |
| BMI (kg/m), median (IQR) | 25.7 (23.4–28.7) | nt | 24.7 (22.3–27.6) | 24.2 (2.8)& | nt | nt | 26 (24–30) |
| BMI ≥30 kg/m, n (%) | 104 (17.2) | nt | 426 (11.3) | 125 (5.5) | 2029 (18.1) | 565 (17) | 11.808 (20.4) |
| CKDepi eGFR (mL/min/1.73 m), median (IQR) | 98 (88–107) | nt | 96 (86–106) | 105 (14)& | nt | nt | 95 (82–108) |
| Low eGFR (mL/min/1.73 m), n (%) | nt | Low for age: 3.4 | nt | nt | nt | ||
| Hypertension, n (%) | 166 (24.1) | nt | nt | 106 (4.7) | nt | 334 (10.3) | 1921 (3.3) |
| Smoking, n (%) | 190 (31.4) | nt | nt | 571 (41.5) | nt | 1266 (38.9) | 15563 (26.8) |
| Biologically related, n (%) | 376 (62.0) | 4103 (50.5) | 62.1 | 1519 (79.9) | 6890 (59.2) | nt | 28488 (49.1) |
| * 367 marginal donors were excluded; # age in categories, number (percentage); & mean and standard deviation; nt – not reported. ANZDATA – Australian and New Zealand Living Kidney Donor Registry; CKDepi – Chronic Kidney Disease Epidemiology Collaboration; eGFR – estimated glomerular filtration rate; NHSBT – National Health Service Blood And Transplant; IQR – interquartile range; n – number; SRTR – Scientific Registry of Transplant Recipients; UK – United Kingdom; US – United States. | |||||||