10 August 2021 : Original article
The Low Utilization Rate of Donor Lungs in China: A Single-Center Experience
Jin Zhao1ABCEF, Dong Liu1AB, Jian Huang1B, Hua-chi Jiang1B, Yuan Chen1B, Hui-xing Li1B, Xiao-shan Li2CD, Jing-yu Chen1AG*DOI: 10.12659/AOT.931409
Ann Transplant 2021; 26:e931409
Table 4 Comparison of donor characteristics, assessment findings, and validity rates between the 2 groups in stage 2.
| Variables | Group A (n=123) | Group B (n=94) | P |
|---|---|---|---|
| Donor characteristics | |||
| Age(years), mean±SD | 37.0±11.1 | 38.2±10.2 | 0.45 |
| Female, n (%) | 24 (19.5) | 18 (19.1) | 0.946 |
| Intubation time(days), median (IQR) | 6 (4–9) | 4 (3–7) | <0.001 |
| Donor lung assessment | |||
| PaO/FiO (mmHg), median (IQR) | 445.0 (383.0–530.0) | 404.5 (278.0–472.3) | 0.003 |
| PaO/FiO <300 mmHg, n (%) | 7 (5.7) | 15 (16.0) | 0.013 |
| Abnormal chest X-ray/CT, n (%) | 13 (10.6) | 21 (22.3) | 0.018 |
| Edema | 2 | 12 | 0.001 |
| Infiltrates/contusion | 10 | 21 | 0.003 |
| Extensive atelectasis | 4 | 2 | 0.7 |
| Pulmonary emphysema | 1 | 1 | 1 |
| Pulmonary thromboembolism | 1 | 0 | 1 |
| Abnormal bronchoscopy, n (%) | 9 (7.3) | 21 (22.3) | 0.001 |
| Mucopurulent secretions | 7 | 20 | 0.001 |
| Aspiration | 2 | 1 | 1 |
| Pan-drug-resistant bacteria, n (%)a | 6 (6.1) | 4 (7.5) | 1 |
| Serological indicator, median (IQR) | |||
| WBC (10/L) | 11.9 (9.1–16.4) | 12.9 (9.4–17.7) | 0.602 |
| PCT (ug/L) | 0.8 (0.2–3.1) | 0.7 (0.2–3.0) | 0.791 |
| CRP (mg/L) | 63.9 (27.1–128.0) | 111.5 (33.4–153.5) | 0.218 |
| Interval between online notification and donation operation (h), median (IQR)b | 20.5 (18.0–26.5) | 13.5 (9.2–19.5) | 0.005 |
| Interval between the first on-site assessment and donation operation (h), median (IQR)b | 11.5 (7.5–14.3) | 6.0 (4.3–9.8) | 0.03 |
| Overallc | 90 (67.7) | 50 (34.7) | <0.001 |
| Stage 1 (% of overall) | 123 (92.5) | 94 (65.3) | <0.001 |
| Stage 2 (% of stage 1) | 95 (77.2) | 60 (63.8) | 0.03 |
| Stage 3 (% of stage 2) | 90 (94.7) | 50 (83.3) | 0.019 |
| Group A: donor lungs from medical institutions with lung transplant qualification; group B: medical institutions without qualification. a Number of cases, group A=98, group B=53; b Number of cases, group A=87, group B=41; c Number of cases, group A=133, group B=144. CT – computed tomography; WBC – white blood cell count; PCT – plateletcrit; CRP – C-reactive protein; IQR – interquartile range; SD – standard deviation. | |||