20 August 2021: Original Paper
Color Doppler Ultrasound and Hemodynamics for Evaluating Graft Dysfunction in Recurrent Immunoglobulin A Nephropathy
Jin Zhang 12ABCDEF* , Guo-Dong Chen 2ABCEF* , Jiang Qiu 2AFG* , Yang Tan 3ABCD , Guo-Chang Liu 1AFG , Li-Zhong Chen 2AG , Wei Jia 1ABD , Wen Fu 1ABD , Chang-Xi Wang 2AGDOI: 10.12659/AOT.931736
Ann Transplant 2021; 26:e931736
Table 1 Baseline characteristics of the recipients and donors.
| Variables* | |
|---|---|
| Recipient age (years) | 34 (28–39) |
| Recipient sex, F/M (%) | 17/61 (22/78) |
| Recipient race, East Asian (%) | 78 (100) |
| Diabetes (%) | 12 (15.4) |
| SBP (mmHg) | 121 (108–137) |
| DBP (mmHg) | 72 (65–83) |
| Acute rejection (%)** | 7 (9.2) |
| Delayed graft function (%) | 4 (5.2) |
| Anti-HLA antibodies (%)# | 13 (17.1) |
| Class I (%) | 5 (6.6) |
| Class II (%) | 13 (17.1) |
| HLA mismatches (A, B, or DR) | 2 (1–3) |
| Therapeutic regimen | |
| Intravenous methylprednisolone pulses (%)## | 21 (27.6) |
| Tonsillectomy (%) | 10 (13.1) |
| ACEIs used (%) | 59 (77.6) |
| Disease time (years)& | 3 (1–5) |
| Waiting time (months)&& | 1 (1–1) |
| 24-h urinary protein (g/24 h) | 0.5 (0.3–1.4) |
| Urinary RBC count (u/ml) | 21.4 (6.7–64.2) |
| Cholesterol (mmol/L) | 5.3 (4.3–6.2) |
| LDL (mmol/L) | 3.4 (2.9–4.2) |
| ALB (g/L) | 41.1 (37.3–44.9) |
| eGFR$ (mL/min/1.73 m) | 69.7 (53.7–84.5) |
| Donor age (years) | 52 (43–57) |
| Donor sex F/M (%) | 55/23 (70/30) |
| Donor race, East Asian (%) | 78 (100) |
| SBP – systolic blood pressure; DBP – diastolic blood pressure; HLA – human leukocyte antigen; ACEIs – angiotensin-converting enzyme inhibitors; RBC – red blood cell; LDL – low-density lipoprotein; ALB – albumin; eGFR – estimated glomerular filtration rate. * All continuous variables were presented as medians and interquartile ranges; ** patients with a history of acute rejection after transplantation were included if they were cured when diagnosed as IgAN. # Including donor-specific antibodies and non-donor specific antibodies; ## three intravenous methylprednisolone pulses at the beginning of recurrence, but routine anti-rejection treatments after transplantation were excluded. & The time from transplantation to the onset of initial symptoms; && the time from the onset of the initial symptoms to biopsy. $ Baseline eGFR after transplantation. | |