14 May 2021>: Original Paper
Nationwide Survey of Post-Transplant Glomerular Diseases, Based on the Japan Renal Biopsy Registry (J-RBR)
Joichi Usui 1ABCDEFG* , Kunihiro Yamagata 1ABCDE , Michio Nagata 2ABCDE , Akira Shimizu 3BDE , Asami Takeda 4BDE , Hitoshi Sugiyama 5BDE , Hiroshi Sato 6BDE , Hitoshi Yokoyama 7BDEDOI: 10.12659/AOT.931873
Ann Transplant 2021; 26:e931873
Table 1 Clinicopathological characteristics of renal allograft biopsies.
Baseline | Protocol | Episode | Unknown | Total | ||
---|---|---|---|---|---|---|
Number | (n) | 9 | 216 | 232 | 220 | 637 |
Age | (Average±SD years) | 45.8±20.0 | 43.5±13.6 | 42.3±14.5 | 38.4±16.9 | 41.3±15.4 |
Sex | (Male: Female) | 6:3 | 102:74 | 162:70 | 133:87 | 403:234 |
Urinary protein | – | 7 | 73 | 75 | 111 | 266 |
± | 0 | 66 | 45 | 37 | 148 | |
1+ | 1 | 30 | 70 | 35 | 136 | |
2+ | 1 | 3 | 27 | 22 | 53 | |
3+ | 0 | 4 | 14 | 10 | 28 | |
4+ | 0 | 0 | 1 | 5 | 6 | |
Hematuria | – | 7 | 125 | 130 | 133 | 395 |
± | 1 | 16 | 27 | 26 | 70 | |
1+ | 1 | 14 | 17 | 15 | 47 | |
2+ | 0 | 9 | 36 | 18 | 63 | |
3+ | 0 | 12 | 22 | 28 | 62 | |
Serum creatinine | (Average±SD mg/dL) | 7.8±3.7 | 1.4±0.3 | 2.5±2.0 | 2.3±2.0 | 2.2±1.9 |
Pathological diagnosis | Glomerular disease | 8 | 23 | 59 | 37 | 127 |
Rejection | 0 | 56 | 114 | 65 | 235 | |
CNI nephropathy | 0 | 14 | 42 | 24 | 80 | |
IF/TA | 0 | 10 | 5 | 29 | 44 | |
CNI – calcineurin inhibitors, IF/TA – interstitial fibrosis and tubular atrophy. |