Can Microscopic Biliary Reconstruction Reduce Biliary Complication Rate in ABO-Incompatible Adult Living Donor Liver Transplantation?

Yu-Cheng Lin; Tsan-Shiun Lin; Chih-Che Lin; Yueh-Wei Liu; Shih-Ho Wang; Yi-Ju Wu; Wei-Feng Li; Yu-Hung Lin; Ting-Lung Lin; Yi-Chia Chan; Cheng-Hsi Yeh; Chih-Chi Wang; Chao-Long Chen; Chee-Chien Yong

doi:10.12659/AOT.931963

27 August 2021 : Original article

Can Microscopic Biliary Reconstruction Reduce Biliary Complication Rate in ABO-Incompatible Adult Living Donor Liver Transplantation?

Yu-Cheng Lin^1BCDEF, Tsan-Shiun Lin^1ABCDF, Chih-Che Lin^1ABCDEF, Yueh-Wei Liu^1B, Shih-Ho Wang^1B, Yi-Ju Wu^1B, Wei-Feng Li^1B, Yu-Hung Lin^1BCDEF, Ting-Lung Lin^1B, Yi-Chia Chan^1B, Cheng-Hsi Yeh^1B, Chih-Chi Wang^1B, Chao-Long Chen^1ABDEF, Chee-Chien Yong^1ABCDEF*

DOI: 10.12659/AOT.931963

Ann Transplant 2021; 26:e931963

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Table 6 Univariate analysis of the risk factors for biliary complications in 90 living donor liver transplantation patients.

	Biliary complication (n=21)	No-biliary complication (n=69)	p Value
Age (years)	54.9±6.76	54.2±7.20	0.71
Male/Female	17/4	58/11	0.74
BMI	24 (21–34)	24 (17–34)	0.82
Disease			0.55
HBV	7 (33.3%)	34 (49.3%)
HCV	6 (28.6%)	21 (30.4%)
PBC	1 (4.8%)	2 (2.9%)
Alcoholic	5 (23.8%)	9 (13%)
Others	2 (9.5%)	3 (4.3%)
HCC	11 (52.4%)	34 (49.3%)	0.80
MELD	10 (6~21)	11 (6~22)	0.97
ABO incompatible	12 (57.1%)	18 (26.1%)	0.01
GRWR (%)	0.93±0.19%	1.08±1.22%	0.58
Graft type			0.06
Right lobe	11 (52.4%)	51 (73.9%)
Left lobe	10 (47.6%)	18 (26.1%)
Biliary reconstruction type			0.10
Duct to duct	21 (100%)	61 (88.4%)
Duct to jejunum	0	8 (11.6%)
No. of Biliary anastomosis			0.08
Single	12 (57.1%)	53 (76.8%)
Multiple	9 (42.9%)	16 (23.2%)
Warm ischemic time	40 min (30–199)	42 min (24–71)	0.62
Cold ischemic time	40 min (25–54)	40 min (18–124)	0.79
Operation time	592 min (540–848)	602 min (431–937)	0.62
Blood loss	2600 ml (600–38200)	2200 ml (150–19600)	0.62
ACR within 1 years	3 (23.8%)	15 (21.7%)	0.84
ALDLT – adult living donor liver transplantation; PBC – primary biliary cholangitis; HCC – hepatocellular carcinoma; MELD score – model for end-stage liver disease; GRWR – graft-to-recipient weight ratio; ACR – acute cellular rejection.

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Can Microscopic Biliary Reconstruction Reduce Biliary Complication Rate in ABO-Incompatible Adult Living Donor Liver Transplantation?

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