27 August 2021: Original Paper
Can Microscopic Biliary Reconstruction Reduce Biliary Complication Rate in ABO-Incompatible Adult Living Donor Liver Transplantation?
Yu-Cheng Lin BCDEF , Tsan-Shiun Lin ABCDF , Chih-Che Lin ABCDEF , Yueh-Wei Liu B , Shih-Ho Wang B , Yi-Ju Wu B , Wei-Feng Li B , Yu-Hung Lin BCDEF , Ting-Lung Lin B , Yi-Chia Chan B , Cheng-Hsi Yeh B , Chih-Chi Wang B , Chao-Long Chen ABDEF , Chee-Chien Yong ABCDEF*DOI: 10.12659/AOT.931963
Ann Transplant 2021; 26:e931963
Table 6 Univariate analysis of the risk factors for biliary complications in 90 living donor liver transplantation patients.
| Biliary complication (n=21) | No-biliary complication (n=69) | p Value | |
|---|---|---|---|
| Age (years) | 54.9±6.76 | 54.2±7.20 | 0.71 |
| Male/Female | 17/4 | 58/11 | 0.74 |
| BMI | 24 (21–34) | 24 (17–34) | 0.82 |
| Disease | 0.55 | ||
| HBV | 7 (33.3%) | 34 (49.3%) | |
| HCV | 6 (28.6%) | 21 (30.4%) | |
| PBC | 1 (4.8%) | 2 (2.9%) | |
| Alcoholic | 5 (23.8%) | 9 (13%) | |
| Others | 2 (9.5%) | 3 (4.3%) | |
| HCC | 11 (52.4%) | 34 (49.3%) | 0.80 |
| MELD | 10 (6~21) | 11 (6~22) | 0.97 |
| ABO incompatible | 12 (57.1%) | 18 (26.1%) | 0.01 |
| GRWR (%) | 0.93±0.19% | 1.08±1.22% | 0.58 |
| Graft type | 0.06 | ||
| Right lobe | 11 (52.4%) | 51 (73.9%) | |
| Left lobe | 10 (47.6%) | 18 (26.1%) | |
| Biliary reconstruction type | 0.10 | ||
| Duct to duct | 21 (100%) | 61 (88.4%) | |
| Duct to jejunum | 0 | 8 (11.6%) | |
| No. of Biliary anastomosis | 0.08 | ||
| Single | 12 (57.1%) | 53 (76.8%) | |
| Multiple | 9 (42.9%) | 16 (23.2%) | |
| Warm ischemic time | 40 min (30–199) | 42 min (24–71) | 0.62 |
| Cold ischemic time | 40 min (25–54) | 40 min (18–124) | 0.79 |
| Operation time | 592 min (540–848) | 602 min (431–937) | 0.62 |
| Blood loss | 2600 ml (600–38200) | 2200 ml (150–19600) | 0.62 |
| ACR within 1 years | 3 (23.8%) | 15 (21.7%) | 0.84 |
| ALDLT – adult living donor liver transplantation; PBC – primary biliary cholangitis; HCC – hepatocellular carcinoma; MELD score – model for end-stage liver disease; GRWR – graft-to-recipient weight ratio; ACR – acute cellular rejection. | |||