30 July 2021 : Original article
Clinical Outcomes of Ablation Compared with Resection for Single Hepatocellular Carcinoma Lesions, as a Primary Treatment or Bridging to Liver Transplantation: A Retrospective Comparative Study
Elizabeth M. Ward1ABCDEF, Ahmed Elshawadfy Sherif12BCDEF*, Stephen O'Neill3CD, Michael Hughes1B, Hamish Ireland4DE, Stephen J. Wigmore1ADE, Anya Adair1ADEDOI: 10.12659/AOT.931980
Ann Transplant 2021; 26:e931980
Table 1 Characteristics of the study groups before and after matching.
| Variable | Before PSM | After PSM | ||||
|---|---|---|---|---|---|---|
| AT (n=92) | SR (n=70) | P value | AT (n=38) | SR (n=38) | P value | |
| * | 66.4±10.3 | 64.7±11.7 | 0.35 | 67.1±11.5 | 65.5±8.1 | 0.38 |
| Male | 68 (73.9%) | 54 (77.1%) | 0.64 | 31 (81.6%) | 34 (89.5%) | 0.55 |
| Female | 24 (26.1%) | 16 (22.9%) | 7 (18.4%) | 4 (10.5%) | ||
| 0.025*** | 0.84 | |||||
| Hepatitis C virus | 29 (31.5%) | 19 (27.1%) | 13 (34.2%) | 16 (42.1%) | ||
| Hepatitis B virus | 2 (2.2%) | 5 (7.1%) | 2 (5.3%) | 2 (5.3%) | ||
| Non-Alcoholic fatty liver disease | 20 (21.7%) | 10 (14.3%) | 6 (15.8%) | 4 (10.5%) | ||
| Alcoholic liver disease | 22 (23.9%) | 12 (17.1%) | 10 (26.3%) | 9 (23.7%) | ||
| Hemochromatosis | 9 (9.8%) | 6 (8.6%) | 3 (7.9%) | 3 (7.9%) | ||
| Autoimmune hepatitis | 4 (4.3%) | 3 (4.3%) | 1 (2.6%) | 2 (5.3%) | ||
| Alpha-1-antitrypsin | 2 (2.2%) | 0 (0.0%) | 2 (5.3%) | 0 (0.0%) | ||
| No/unknown background liver disease | 4 (4.3%) | 15 (21.4%) | 1 (2.6%) | 2 (5.3%) | ||
| ** | 20 (15–25) | 33.5 (20–65) | *** | 20 (14–24) | 21.5 (14–25) | 0.30 |
| * | 48.3±2.9 | 46.5±2.1 | *** | 47.3±2.5 | 47.3±1.9 | 0.90 |
| ** | 6 (3–16) | 8 (3–19) | 0.83 | 5 (3–10) | 9 (3–21) | 0.47 |
| * Parametric variables presented with mean±SD. ** Nonparametric variables presented with median (interquartile range). *** Significant at 0.05 probability level. | ||||||