26 November 2021>: Original Paper
Validation of Accuracy of Non-Invasive Imaging Methods (Magnetic Resonance Imaging (MRI) Fat Fraction Calculation and Computed Tomography (CT) Liver Attenuation Index) for Hepatic Graft Fat Quantification in Living Liver Transplant Donors
Abhideep Chaudhary 1ABE , Gaurav Sood 1BD , Niteen Kumar 1BF , Chandraprakash Chauhan 2EF , Dhirendra Pratap Singh Yadav 2CD , Vivek Kasana 3BCF , Raman Arora 4CD , Gaurav Gangwani 5ABCDEF*DOI: 10.12659/AOT.933801
Ann Transplant 2021; 26:e933801
Table 4 Sensitivity, specificity, PPV, and NPV of MRCP fat (%) and CT-LAI for predicting significant fat.
Biopsy-macrosteatosis (%) | MRCP Fat(%) (>10%) | MRCP Fat(%) (>15%) | CT-LAI |
---|---|---|---|
Sensitivity (95% CI) | 54.55% (23.38% to 83.25%) | 0% (0.00% to 84.19%) | 100% (15.81% to 100.00%) |
Specificity (95% CI) | 96.95% (94.07% to 98.67%) | 99.26% (97.36% to 99.91%) | 71.22% (65.43% to 76.53%) |
AUC (95% CI) | 0.76 (0.70 to 0.81) | 0.5 (1.00 to 1.00) | 0.86 (0.81 to 0.90) |
Positive predictive value (95% CI) | 42.86% (17.66% to 71.14%) | 0% (0.00% to 84.19%) | 2.5% (0.30% to 8.74%) |
Negative predictive value (95% CI) | 98.07% (95.55% to 99.37%) | 99.26% (97.36% to 99.91%) | 100% (98.11% to 100.00%) |
Diagnostic accuracy | 95.24% | 98.53% | 71.43% |