01 December 2021 : Original article
Solid-Phase C1q/C3d Fixing Readouts Correlate with High Median Fluorescence Intensity (MFI) De Novo Donor-Specific HLA Antibodies and C4d⁺ Antibody-Mediated Rejection in Kidney Transplant Recipients
Vasishta S. Tatapudi1BDEF, Dessislava Kopchaliiska2ABC, Gilberto J. da Gente2C, Owen F. Buenaventura2BC, Manpreet Singh3BC, Zoltan Laszik4BC, Deborah B. Adey1CDE, Raja Rajalingam
2ADEF*
DOI: 10.12659/AOT.934175
Ann Transplant 2021; 26:e934175
Table 1 Demographic and clinical characteristics of kidney transplant recipients developing de novo donor-specific HLA antibodies (n=120).
| % (n)/Mean±SD | |
|---|---|
| Age at transplantation (y) | 47±18 years |
| Gender; Female | 40% (48) |
| Ethnicity/Race | |
| Caucasian | 40% (48) |
| African-American | 29% (35) |
| Asian | 26% (31) |
| Hispanic/Latino | 5% (6) |
| Blood type | |
| A | 42% (50) |
| B | 10% (12) |
| O | 43% (52) |
| AB | 5% (6) |
| Pre-tx CPRA | |
| 0–9% | 28% (34) |
| 10–79% | 51% (61) |
| 80+% | 21% (25) |
| Primary transplantation | 86% (103) |
| Re-transplantation | 14% (17) |
| Age (y) | 41±15 |
| Gender; Female | 42% (50) |
| Living donor | 30% (36) |
| Deceased donor | 70% (84) |
| Kidney only | 91% (109) |
| Kidney and Pancreas | 9% (11) |
| Number of HLA-A/B/Cw/DR/DQ MM | 7.7±2.3 |