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01 December 2021 : Original article  

Solid-Phase C1q/C3d Fixing Readouts Correlate with High Median Fluorescence Intensity (MFI) De Novo Donor-Specific HLA Antibodies and C4d⁺ Antibody-Mediated Rejection in Kidney Transplant Recipients

Vasishta S. Tatapudi1BDEF, Dessislava Kopchaliiska2ABC, Gilberto J. da Gente2C, Owen F. Buenaventura2BC, Manpreet Singh3BC, Zoltan Laszik4BC, Deborah B. Adey1CDE, Raja Rajalingam ORCID logo2ADEF*

DOI: 10.12659/AOT.934175

Ann Transplant 2021; 26:e934175

Table 1 Demographic and clinical characteristics of kidney transplant recipients developing de novo donor-specific HLA antibodies (n=120).

% (n)/Mean±SD
Age at transplantation (y)47±18 years
Gender; Female40% (48)
Ethnicity/Race
 Caucasian40% (48)
 African-American29% (35)
 Asian26% (31)
 Hispanic/Latino5% (6)
Blood type
 A42% (50)
 B10% (12)
 O43% (52)
 AB5% (6)
Pre-tx CPRA
 0–9%28% (34)
 10–79%51% (61)
 80+%21% (25)
Primary transplantation86% (103)
Re-transplantation14% (17)
Age (y)41±15
Gender; Female42% (50)
Living donor30% (36)
Deceased donor70% (84)
Kidney only91% (109)
Kidney and Pancreas9% (11)
Number of HLA-A/B/Cw/DR/DQ MM7.7±2.3

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358