Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

26 January 2022: Review Paper

Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models

Wojciech Andrzej Straś 1AEF , Dariusz Wasiak 1F , Beata Łągiewska 2F , Olga Tronina 3EF* , Marta Hreńczuk 1F , Joanna Gotlib 4F , Wojciech Lisik 2AF , Piotr Małkowski 1AEFG

DOI: 10.12659/AOT.934924

Ann Transplant 2022; 27:e934924

Table 1 Risk factors predicting hepatocellular carcinoma before and after liver transplantation.

Risk factorsRef.
Risk factors before transplantation✓ Numer and size of the nodules[,,]19
✓ Vascular invasion[,]11
✓ Alpha-Fetoprotein level[,,]27
✓ Neutrophil-lymphocyte ratio[,,,–]19
✓ Positron emission tomography scan/magnetic resonance imaging[,–]19
✓ Bridging therapy response[,,,–]8
✓ Metabolic syndrome, obesity[–]54
✓ HBV and HCV viral infections[–]64
✓ Biopsy[–]85
✓ Time to transplantation17, 88–89
Post-transplantation risk factors✓ Degree of tumor differentiation, vascular invasion[,–]11
✓ Liver donor[–]92
✓ Cold ischemia time[–]96
✓ Operating technique[,]99
✓ Immunosuppression[–]101
✓ Adjuvant treatment[,–]21

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358