07 June 2022 : Original article
Phosphatidylethanol (PEth) for Monitoring Sobriety in Liver Transplant Candidates: Preliminary Results of Differences Between Alcohol-Related and Non-Alcohol-Related Cirrhosis Candidates
Jan-Paul Gundlach1EF*, Felix Braun1AD, Finn Mötter1B, Alexander Bernsmeier1CDE, Pablo Barrio2E, Nicola Ehmke1B, Rainer Günther3B, Holger Hinrichsen4A, Thomas Becker1AD, Wolfgang Weinmann
5B, Alexandra Schröck6C, Michel Yegles7C, Friedrich Martin Wurst8ACDE
DOI: 10.12659/AOT.936293
Ann Transplant 2022; 27:e936293
Table 1 Patient characteristics, biomarker values, and follow-up data, showing the number of patients (n), range, mean value and standard deviation (SD) for demographic parameters, expression of liver values, and AUDIT results, as well as number of positive test results, range, mean value and SD for uEtG, hEtG, PEth (16: 0/18: 2), and realized liver transplantations (LT) within the follow-up period for the total group as well as for the biomarker groups.
| Agen=66 | ASAT (U/L) n=66 | ALAT (U/L) n=66 | μGT (U/L) n=66 | MCV (fl) n=66 | AUDITn=66 | uEtG (mg/L) n=65 | hEtG (pg/mg) n=65 | PEth (ng/mL) n=66 | |
|---|---|---|---|---|---|---|---|---|---|
| Positive results (%) | 5 (7.7) | 9 (13.8) | 34 (51.5) | ||||||
| Min | 21.0 | 17.4 | 6.8 | 14.0 | 29.0 | 0.0 | 0.20 | 7.3 | 20.6 |
| Max | 74.0 | 229.0 | 313.9 | 1034.0 | 98.7 | 16.0 | 3.6 | 78.0 | 606.0 |
| Mean | 53.3 | 57.1 | 43.2 | 132.1 | 84.8 | 2.1 | 1.5 | 40.4 | 89.5 |
| SD | 12.02 | 42.70 | 45.96 | 167.76 | 11.42 | 3.21 | 1.64 | 26.05 | 112.25 |
| LT performed (%) | 23 (34.9) | 1 (20.0) | 4 (44.4) | 9 (26.5) | |||||
| Deaths after LT (%) | 6 (9.1) | 0 (0.0) | 2 (50.0) | 1 (11.1) | |||||
| Deaths without LT (%) | 9 (20.9) | 0 (0.0) | 1 (20.0) | 5 (14.7) | |||||