19 July 2022: Original Paper
Graft Inflow Modulation in Living-Donor Liver Transplantation: Hepatic Hemodynamic Changes in Splenic Artery Ligation and Splenectomy
Che-Min Su ABCDEF , Tsung-Ching Chou ABD , Tsung-Han Yang ABD , Yih-Jyh Lin ABDEF*DOI: 10.12659/AOT.936609
Ann Transplant 2022; 27:e936609
Table 2 Operative characteristics of all recipients and donors.
| VariablesModulation | Group No. | GIM group (SAL+splenectomy) | P-value |
|---|---|---|---|
| N | 63 | 36 (17+19) | |
| Recipient | |||
| Cold ischaemic time, min | 202 (162–240) | 179 (144–210) | 0.016 |
| Anhepatic phase, min | 80 (61–106) | 79 (64–103) | 0.988 |
| Operation time, min | 657 (576–746) | 685 (558–772) | 0.825 |
| Blood loss | 3000 (1500–5850) | 3050 (1850–4400) | 0.760 |
| SFSS | 7 (11.1) | 4 (11.1) | 1.0 |
| EAD | 7 (11.1) | 2 (5.6) | 0.355 |
| Hospital stay | 26 (21–33) | 25 (20–32) | 0.438 |
| ICU stay | 14 (11–21) | 12 (10–16) | 0.048 |
| Severe postoperative complications* | 0.464 | ||
| 3a | 26 (41.3) | 13 (36.1) | |
| 3b | 8 (12.7) | 2 (5.6) | |
| 4a | 4 (6.3) | 1 (2.8) | |
| 4c | 1 (1.6) | 1 (2.8) | |
| Hospital mortality | 4 (6.3) | 1 (2.8) | |
| Specific postoperative complications | |||
| Hepatic artery thrombosis/pseudoaneurysm+ | 1 (1.6) | 1 (2.8) | 0.685 |
| Portal vein thrombosis | 4 (6.3) | 2 (5.6) | 0.874 |
| Hepatic vein thrombosis | 0 | 1 (2.8) | 0.184 |
| Bile leakage/stricture | 14 (22.2) | 6 (16.7) | 0.508 |
| Liver hemodynamics | |||
| Initial portal flow, ml/min/100 g | 156 (115–213) | 311 (252–384) | |
| Initial HA flow, ml/min | 100 (68–134) | 49 (39–80) | |
| Final portal flow, ml/min/100 g | 156 (115–213) | 224 (179–267) | |
| Final HA flow, ml/min | 100 (68–134) | 80 (50–120) | 0.065 |
| SAL – splenic artery ligation; SFSS – small-for-size syndrome; EAD – early allograft dysfunction; ICU – Intensive Care Unit; HA – hepatic artery. * Clavien-Dindo classification. Continuous variables are expressed as the median (IQR). Categorical variables are expressed as number of patients (percentage). | |||