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19 July 2022: Original Paper

Graft Inflow Modulation in Living-Donor Liver Transplantation: Hepatic Hemodynamic Changes in Splenic Artery Ligation and Splenectomy

Che-Min Su ABCDEF , Tsung-Ching Chou ABD , Tsung-Han Yang ABD , Yih-Jyh Lin ABDEF*

DOI: 10.12659/AOT.936609

Ann Transplant 2022; 27:e936609

Table 3 Clinical characteristics of all recipients and donors in the modulation group.

VariablesModulationSubgroup 1SALSubgroup 2SlenectomyP
N1719
Recipient
 Age, years58 (52–64)54 (49–63)0.253
 Sex (M), n (%)14 (82.4)9 (47.4)0.029
 BMI, kg/m24.9 (23.4–26.1)25.4 (22.9–31.2)0.428
 Hepatitis profile0.180
  HBV+/HCV+02 (10.5)
  HBV+10 (58.8)5 (26.3)
  HCV+3 (17.6)5 (26.3)
  Negative4 (23.5)7 (36.8)
 Disease indication, n (%)0.124
  Acute/acute on chronic liver failure3 (17.6)1 (5.3)
  Decompensated cirrhosis6 (35.3)13 (68.4)
  Hepatocellular carcinoma8 (47.1)5 (26.3)
 MELD15 (10–24)14 (12–19)0.799
 MELD ≥25, n (%)4 (23.5)3 (17.6)0.858
 ABO incompatible, n (%)4 (21.1)4 (21.1)0.797
Donor
 Donor age, y26 (23–33)33 (23–37)0.136
 Donor age ≥40, n (%)05 (26.3)0.023
 Sex (M), n (%)11 (64.7)5 (26.3)0.021
 BMI, kg/m20.4 (18.4–23.7)23.2 (21.2–23.6)0.090
Liver graft
 Actual GRWR (%)0.99 (0.84–1.12)0.83 (0.71–0.99)0.038
 GRWR2 (11.8)9 (47.4)0.021
 Graft weight, g658 (575–782)577 (452–682)0.022
 Graft type, n (%)0.74
  Right lobe17 (100)14 (73.7)
  Left lobe04 (21.1)
  Right lobe with MHV00
  Right posterior section01 (5.3)
SAL – splenic artery ligation; BMI – body mass index; HBV – hepatitis B virus; HCV – hepatitis C virus; MELD – model of end-stage liver disease; GRWR – graft-to-recipient weight ratio. Continuous variables are expressed as median (IQR). Categorical variables are expressed as number of patients (percentage).

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358