Leucine-Rich Alpha-2-Glycoprotein (LRG-1) as a Potential Kidney Injury Marker in Kidney Transplant Recipients

Anna Popova; Aiga Vasiļvolfa; Kārlis Rācenis; Renārs Erts; Baiba Šlisere; Anna Jana Saulīte; Ieva Ziedina; Inese Folkmane; Harijs Čerņevskis; Juta Kroiča; Aivars Pētersons; Viktorija Kuzema

doi:10.12659/AOT.936751

06 September 2022 : Original article

Leucine-Rich Alpha-2-Glycoprotein (LRG-1) as a Potential Kidney Injury Marker in Kidney Transplant Recipients

Anna Popova^123ACDE*, Aiga Vasiļvolfa^134ABCDEF, Kārlis Rācenis^12ACD, Renārs Erts^5C, Baiba Šlisere^2BC, Anna Jana Saulīte^12EF, Ieva Ziedina

^14AB, Inese Folkmane^13AB, Harijs Čerņevskis^14DE, Juta Kroiča^2ACDF, Aivars Pētersons^14ACD, Viktorija Kuzema

^14ACDE

DOI: 10.12659/AOT.936751

Ann Transplant 2022; 27:e936751

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Table 3 Diagnostic performance of urine LRG-1.

Parameter	Se (95% CI)	Sp (95% CI)	PPV (95% CI)	NPV (95% CI)	LR+ (95% CI)	LR− (95% CI)
Urine LRG-1 >0.1 ug/ml	0.79 (0.49–0.95)	0.70 (0.46–0.88)	0.65 (0.38–0.86)	0.82 (0.57–0.96)	2.62 (1.27–5.40)	0.31 (0.11–0.87)
Se – sensitivity; Sp – specificity; PPV – positive predictive value, NPV – negative predictive value; LR+ – positive likelihood ratio; LR− – negative likelihood ratio.

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Leucine-Rich Alpha-2-Glycoprotein (LRG-1) as a Potential Kidney Injury Marker in Kidney Transplant Recipients

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