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12 August 2022: Original Paper

Retrospective Study from a Single Center in Romania of 347 Renal Transplant Patients Treated with Tacrolimus, Mycophenolate, and Steroids to Evaluate the Association Between Anti-HLA Antibodies and 5-Year Graft Survival

Ion Mărunţelu 12ABCDEF , Claudiu Eduard Nistor 2CEF* , Bogdan Mihai Cristea 2CE , Corina Andreea Rotarescu 12BCD , Andreea Mirela Caragea 2B , Maria Tizu 2B , Ileana Constantinescu 12AD

DOI: 10.12659/AOT.937267

Ann Transplant 2022; 27:e937267

Table 6 Hazard ratios with 95% confidence interval in patients without preformed anti-HLA antibodies.

FactorNegative HLA antibodiesPositive HLA antibodies
Negative HLA antibodies4.0251
1.5574 to 10.4032
Positive HLA antibodies0.2484
0.09612 to 0.6421
HLA – human leukocyte antigen. In the non-HLA previous sensitized group, the estimated relative risk of the event of kidney graft loss occurring in the subgroup with de novo anti-HLA antibodies is 4.0251 greater than in the subgroup with no HLA antibodies.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358