02 December 2022 : Original article
Pure Laparoscopic Versus Open Right Hepatectomy in Living Liver Donors: Graft Weight Discrepancy
Jiwon Seo1ABCDEF, Suk Kyun Hong1ABCDEF*, Sola Lee1BE, Su young Hong1BE, YoungRok Choi1BE, Nam-Joon Yi1BE, Kwang-Woong Lee1BE, Kyung-Suk Suh1BDDOI: 10.12659/AOT.938274
Ann Transplant 2022; 27:e938274
Table 1 Baseline characteristics and operative outcomes of liver donors who underwent CDRH and PLDRH.
| Variables | CDRH (n=119) | PLDRH (n=376) | P value |
|---|---|---|---|
| Sex | 0.857 | ||
| Male | 72 | 224 | |
| Female | 47 | 152 | |
| Age, years | 36.5±12.7 | 33.6±10.8 | 0.026 |
| BMI, kg/m | 23.3±3.1 | 23.8±3.3 | 0.105 |
| DM | 2 (1.7) | 1 (0.3) | 0.145 |
| HTN | 9 (7.6) | 12 (3.2) | 0.039 |
| ABO compatibility | 0.102 | ||
| Compatible | 104 (87.4) | 304 (80.9) | |
| Incompatible | 15 (12.6) | 72 (19.1) | |
| Abdominal OP history | 24 (20.5) | 63 (16.8) | 0.358 |
| Missing | 2 | 1 | |
| Preoperative blood tests | |||
| Hb, g/dL | 14.8±1.4 | 14.7±1.4 | 0.397 |
| Total bilirubin, mg/dL | 0.5±0.2 | 0.5±0.3 | 0.468 |
| AST, IU/L | 16.6±3.3 | 16.8±3.6 | 0.559 |
| ALT, IU/L | 15.8±6.7 | 15.9±7.3 | 0.871 |
| CT graft variation | 90 (75.6) | 267 (71) | 0.327 |
| Bile duct | 36 (30.3) | 156 (41.5) | 0.028 |
| Portal vein | 23 (19.3) | 70 (18.6) | 0.863 |
| Hepatic artery | 5 (4.2) | 11 (2.9) | 0.552 |
| Right inferior hepatic vein | 70 (58.8) | 159 (42.3) | 0.002 |
| Operative time, minutes | 237.5±48.1 | 260.9±66.1 | <0.001 |
| Warm ischemia time, minutes* | 4±4 | 13±18 | <0.001 |
| Missing | 3 | 7 | |
| Bench work time, minutes | 43.1±18.6 | 59.2±20.6 | <0.001 |
| Missing | 9 | 14 | |
| Blood loss, mL | 300.8±167.1 | 257.8±194.6 | 0.020 |
| Missing | 0 | 2 | |
| Fatty change, % | |||
| Macrovesicular | 2.6±2.6 | 2.0±2.9 | 0.066 |
| Microvesicular | 1.8±2.0 | 1.4±2.9 | 0.170 |
| Missing | 5 | 4 | |
| Graft weight, g | |||
| Estimated graft weight | 792.3±169.9 | 792.2±171.3 | 0.994 |
| Missing | 2 | 0 | |
| Actual graft weight | 712.5±142.0 | 722.9±138.5 | 0.489 |
| Missing | 6 | 1 | |
| HBcAb | 13 (11) | 65 (17.3) | 0.101 |
| Missing | 1 | 1 | |
| Postoperative blood tests | |||
| Hb, g/dL | |||
| Lowest | 11.6±1.3 | 11.7±1.4 | 0.702 |
| ΔHb%** | 21.6±5.1 | 20.4±7.1 | 0.051 |
| Total bilirubin, mg/dL | |||
| Peak | 3.6±1.8 | 4.2±2.0 | 0.004 |
| Δbilirubin%*** | 657.9±389.6 | 847.2±497.8 | <0.001 |
| AST, IU/L | |||
| Peak | 170.5±59.4 | 222.3±92.4 | <0.001 |
| ΔAST%# | 958.0±430.6 | 1244.7±512.9 | <0.001 |
| ALT, IU/L | |||
| Peak | 170.0±67.2 | 232.5±91.0 | <0.001 |
| ΔALT%## | 1100.9±546.3 | 1548.5±788.9 | <0.001 |
| Hospital stays, days | 8.5±1.8 | 7.2±2.4 | <0.001 |
| Postoperative complications### | 5 (4.2) | 27 (7.2) | 0.249 |
| Minor | 2 (1.7) | 10 (2.7) | 0.739 |
| Hyperbilirubinemia | 2 (1.7) | 4 (1.1) | 0.634 |
| Wound | 0 | 3 (0.8) | 1.000 |
| Fluid | 0 | 1 (0.3) | 1.000 |
| Ascites | 0 | 1 (0.3) | 1.000 |
| HV narrowing | 0 | 1 (0.3) | 1.000 |
| Others | 0 | 1 (0.3) | 1.000 |
| Major | 3 (2.5) | 19 (5.1) | 0.243 |
| Bleeding | 0 | 2 (0.5) | 1.000 |
| Bile | 2 (1.7) | 11 (2.9) | 0.743 |
| Infection(anti) | 3 (2.5) | 5 (1.3) | 0.406 |
| Others | 1 (0.8) | 8 (2.1) | 0.694 |
| Data are given as mean±SD or n (%). BMI – body mass index; DM – diabetes mellitus; HTN – hypertension; Hb – hemoglobin; AST – aspartate aminotransferase; ALT – alanine aminotransferase; CT – computed tomography; HBcAb – hepatitis B core antibody; HV – hepatic vein. * Warm ischemia time was defined as the time from hepatic artery ligation to the time when the liver was removed. ** ΔHb% = [(preoperative Hb – postoperative Hb)/preoperative Hb]×100. *** Δbilirubin% = [(preoperative bilirubin – postoperative bilirubin)/preoperative bilirubin]×100. # ΔAST% = [(preoperative AST – postoperative AST)/preoperative AST]×100. ## ΔALT% = [(preoperative ALT – postoperative ALT)/preoperative ALT]×100. ### Major complications were defined as a Clavien-Dindo grade ≥3. | |||