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02 December 2022: Original Paper

Pure Laparoscopic Versus Open Right Hepatectomy in Living Liver Donors: Graft Weight Discrepancy

Jiwon Seo ABCDEF , Suk Kyun Hong ABCDEF , Sola Lee BE , Su young Hong BE , YoungRok Choi BE , Nam-Joon Yi BE , Kwang-Woong Lee BE , Kyung-Suk Suh BD*

DOI: 10.12659/AOT.938274

Ann Transplant 2022; 27:e938274

Table 1 Baseline characteristics and operative outcomes of liver donors who underwent CDRH and PLDRH.

VariablesCDRH (n=119)PLDRH (n=376)P value
Age, years36.5±12.733.6±10.80.026
BMI, kg/m23.3±3.123.8±3.30.105
DM2 (1.7)1 (0.3)0.145
HTN9 (7.6)12 (3.2)0.039
ABO compatibility0.102
 Compatible104 (87.4)304 (80.9)
 Incompatible15 (12.6)72 (19.1)
Abdominal OP history24 (20.5)63 (16.8)0.358
Preoperative blood tests
 Hb, g/dL14.8±1.414.7±1.40.397
 Total bilirubin, mg/dL0.5±0.20.5±0.30.468
 AST, IU/L16.6±3.316.8±3.60.559
 ALT, IU/L15.8±6.715.9±7.30.871
CT graft variation90 (75.6)267 (71)0.327
 Bile duct36 (30.3)156 (41.5)0.028
 Portal vein23 (19.3)70 (18.6)0.863
 Hepatic artery5 (4.2)11 (2.9)0.552
 Right inferior hepatic vein70 (58.8)159 (42.3)0.002
Operative time, minutes237.5±48.1260.9±66.1
Warm ischemia time, minutes* 4±413±18
Bench work time, minutes43.1±18.659.2±20.6
Blood loss, mL300.8±167.1257.8±194.60.020
Fatty change, %
Graft weight, g
 Estimated graft weight792.3±169.9792.2±171.30.994
 Actual graft weight712.5±142.0722.9±138.50.489
HBcAb13 (11)65 (17.3)0.101
Postoperative blood tests
 Hb, g/dL
 ΔHb%** 21.6±5.120.4±7.10.051
 Total bilirubin, mg/dL
 Δbilirubin%*** 657.9±389.6847.2±497.8
 ΔAST%# 958.0±430.61244.7±512.9
 ΔALT%## 1100.9±546.31548.5±788.9
Hospital stays, days8.5±1.87.2±2.4
Postoperative complications### 5 (4.2)27 (7.2)0.249
 Minor2 (1.7)10 (2.7)0.739
 Hyperbilirubinemia2 (1.7)4 (1.1)0.634
 Wound03 (0.8)1.000
 Fluid01 (0.3)1.000
 Ascites01 (0.3)1.000
 HV narrowing01 (0.3)1.000
 Others01 (0.3)1.000
 Major3 (2.5)19 (5.1)0.243
 Bleeding02 (0.5)1.000
 Bile2 (1.7)11 (2.9)0.743
 Infection(anti)3 (2.5)5 (1.3)0.406
 Others1 (0.8)8 (2.1)0.694
Data are given as mean±SD or n (%). BMI – body mass index; DM – diabetes mellitus; HTN – hypertension; Hb – hemoglobin; AST – aspartate aminotransferase; ALT – alanine aminotransferase; CT – computed tomography; HBcAb – hepatitis B core antibody; HV – hepatic vein.
* Warm ischemia time was defined as the time from hepatic artery ligation to the time when the liver was removed.
** ΔHb% = [(preoperative Hb – postoperative Hb)/preoperative Hb]×100.
*** Δbilirubin% = [(preoperative bilirubin – postoperative bilirubin)/preoperative bilirubin]×100.
# ΔAST% = [(preoperative AST – postoperative AST)/preoperative AST]×100.
## ΔALT% = [(preoperative ALT – postoperative ALT)/preoperative ALT]×100.
### Major complications were defined as a Clavien-Dindo grade ≥3.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358