02 December 2022>: Original Paper
Pure Laparoscopic Versus Open Right Hepatectomy in Living Liver Donors: Graft Weight Discrepancy
Jiwon Seo ABCDEF , Suk Kyun Hong ABCDEF , Sola Lee BE , Su young Hong BE , YoungRok Choi BE , Nam-Joon Yi BE , Kwang-Woong Lee BE , Kyung-Suk Suh BD*DOI: 10.12659/AOT.938274
Ann Transplant 2022; 27:e938274
Table 1 Baseline characteristics and operative outcomes of liver donors who underwent CDRH and PLDRH.
Variables | CDRH (n=119) | PLDRH (n=376) | P value |
---|---|---|---|
Sex | 0.857 | ||
Male | 72 | 224 | |
Female | 47 | 152 | |
Age, years | 36.5±12.7 | 33.6±10.8 | 0.026 |
BMI, kg/m | 23.3±3.1 | 23.8±3.3 | 0.105 |
DM | 2 (1.7) | 1 (0.3) | 0.145 |
HTN | 9 (7.6) | 12 (3.2) | 0.039 |
ABO compatibility | 0.102 | ||
Compatible | 104 (87.4) | 304 (80.9) | |
Incompatible | 15 (12.6) | 72 (19.1) | |
Abdominal OP history | 24 (20.5) | 63 (16.8) | 0.358 |
Missing | 2 | 1 | |
Preoperative blood tests | |||
Hb, g/dL | 14.8±1.4 | 14.7±1.4 | 0.397 |
Total bilirubin, mg/dL | 0.5±0.2 | 0.5±0.3 | 0.468 |
AST, IU/L | 16.6±3.3 | 16.8±3.6 | 0.559 |
ALT, IU/L | 15.8±6.7 | 15.9±7.3 | 0.871 |
CT graft variation | 90 (75.6) | 267 (71) | 0.327 |
Bile duct | 36 (30.3) | 156 (41.5) | 0.028 |
Portal vein | 23 (19.3) | 70 (18.6) | 0.863 |
Hepatic artery | 5 (4.2) | 11 (2.9) | 0.552 |
Right inferior hepatic vein | 70 (58.8) | 159 (42.3) | 0.002 |
Operative time, minutes | 237.5±48.1 | 260.9±66.1 | |
Warm ischemia time, minutes* | 4±4 | 13±18 | |
Missing | 3 | 7 | |
Bench work time, minutes | 43.1±18.6 | 59.2±20.6 | |
Missing | 9 | 14 | |
Blood loss, mL | 300.8±167.1 | 257.8±194.6 | 0.020 |
Missing | 0 | 2 | |
Fatty change, % | |||
Macrovesicular | 2.6±2.6 | 2.0±2.9 | 0.066 |
Microvesicular | 1.8±2.0 | 1.4±2.9 | 0.170 |
Missing | 5 | 4 | |
Graft weight, g | |||
Estimated graft weight | 792.3±169.9 | 792.2±171.3 | 0.994 |
Missing | 2 | 0 | |
Actual graft weight | 712.5±142.0 | 722.9±138.5 | 0.489 |
Missing | 6 | 1 | |
HBcAb | 13 (11) | 65 (17.3) | 0.101 |
Missing | 1 | 1 | |
Postoperative blood tests | |||
Hb, g/dL | |||
Lowest | 11.6±1.3 | 11.7±1.4 | 0.702 |
ΔHb%** | 21.6±5.1 | 20.4±7.1 | 0.051 |
Total bilirubin, mg/dL | |||
Peak | 3.6±1.8 | 4.2±2.0 | 0.004 |
Δbilirubin%*** | 657.9±389.6 | 847.2±497.8 | |
AST, IU/L | |||
Peak | 170.5±59.4 | 222.3±92.4 | |
ΔAST%# | 958.0±430.6 | 1244.7±512.9 | |
ALT, IU/L | |||
Peak | 170.0±67.2 | 232.5±91.0 | |
ΔALT%## | 1100.9±546.3 | 1548.5±788.9 | |
Hospital stays, days | 8.5±1.8 | 7.2±2.4 | |
Postoperative complications### | 5 (4.2) | 27 (7.2) | 0.249 |
Minor | 2 (1.7) | 10 (2.7) | 0.739 |
Hyperbilirubinemia | 2 (1.7) | 4 (1.1) | 0.634 |
Wound | 0 | 3 (0.8) | 1.000 |
Fluid | 0 | 1 (0.3) | 1.000 |
Ascites | 0 | 1 (0.3) | 1.000 |
HV narrowing | 0 | 1 (0.3) | 1.000 |
Others | 0 | 1 (0.3) | 1.000 |
Major | 3 (2.5) | 19 (5.1) | 0.243 |
Bleeding | 0 | 2 (0.5) | 1.000 |
Bile | 2 (1.7) | 11 (2.9) | 0.743 |
Infection(anti) | 3 (2.5) | 5 (1.3) | 0.406 |
Others | 1 (0.8) | 8 (2.1) | 0.694 |
Data are given as mean±SD or n (%). BMI – body mass index; DM – diabetes mellitus; HTN – hypertension; Hb – hemoglobin; AST – aspartate aminotransferase; ALT – alanine aminotransferase; CT – computed tomography; HBcAb – hepatitis B core antibody; HV – hepatic vein. * Warm ischemia time was defined as the time from hepatic artery ligation to the time when the liver was removed. ** ΔHb% = [(preoperative Hb – postoperative Hb)/preoperative Hb]×100. *** Δbilirubin% = [(preoperative bilirubin – postoperative bilirubin)/preoperative bilirubin]×100. # ΔAST% = [(preoperative AST – postoperative AST)/preoperative AST]×100. ## ΔALT% = [(preoperative ALT – postoperative ALT)/preoperative ALT]×100. ### Major complications were defined as a Clavien-Dindo grade ≥3. |