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03 March 2023: Original Paper

Comparison of Biosimilar Filgrastim with Innovator Fligrastim for Peripheral Blood Stem Cells Mobilization, Collection of CD34+ Stem Cells, and Engraftment in Patients Undergoing Autologous and Allogeneic Stem Cell Transplantation: A Single-Center Experience

Maha M. Islami 1CDE* , Mansoor Ahmed Khan 23ABCDEF , Mohammed A. Aseeri 23A , Majed A. Alshamrani 23E , Abdelmajid Alnatsheh 23ACDE , Sameer Alamoudi 34ADE , Ahmed A. Alzahrani 5E

DOI: 10.12659/AOT.938585

Ann Transplant 2023; 28:e938585

Table 2 Mobilization results.

ParametersZarzio®Neupogen®P value
AutologousTime to successful harvest
 Filgrastim + chemotherapy14150.477
CD34+ ×10/kg
 Filgrastim + chemotherapy55.50.641
Allogeneic (healthy donors)Time to successful harvest440.576
CD34+ ×10/kg6.44560.347

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358