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21 April 2023: Original Paper

Converting from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in Patients with Hepatitis B Following Liver Transplantation

Chih-Hsien Cheng ABCDE , Hao-Chien Hung BC , Jin-Chiao Lee BC , Yu-Chao Wang CD , Tsung-Han Wu CD , Chen-Fang Lee ABC , Ting-Jung Wu BC , Hong-Shiue Chou BC , Kun-Ming Chan BC , Wei-Chen Lee ABCD*

DOI: 10.12659/AOT.938731

Ann Transplant 2023; 28:e938731

Table 2 Patients with HBV recurrence.

PatientTime to recurrence (years)Post-transplant antiviral therapyAntiviral therapy after HBV recurrenceHBV DNA at recurrence (IU/ml)YIDD mutationHBsAg declineHBsAg prezent (IU/ml)HBV DNA AT prezent (IUI/ml)CKD stage before TDFCKD stage before TAF
912LAM+ADVLAM+TDF1.7×10Yesseq 552No48Undetec-table22
156LAM+ADVTDF2115Yesseq 55256Undetec-table11
HBV – hepatitis B virus; LAM – lamivudine; ADV – adefovir; ETV – entecavir; TBV – telbivudine; TDF – tenofovir disoproxil fumarate; TAF – tenofovir alafenamide; CKD – chronic kidney disease; Seq – sequence.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358