30 May 2023: Case Report
Outcomes from a Single Transplant Center of 5 Pediatric Cases of Domino Liver Transplantation from Live Donors with Maple Syrup Urine Disease
Jin-Ping Zhang 12ABCDEFG , Zhi-Jun Zhu 12AF* , Li-Ying Sun 123EFG , Lin Wei 12AG , Wei Qu 12CG , Zhi-Gui Zeng 12CD , Hai-Ming Zhang 12CE , Ying Liu 123BDDOI: 10.12659/AOT.939893
Ann Transplant 2023; 28:e939893
Table 5 DLT from live donors with MSUD.
| Corresponding author | Patient Number | Age of patient (y) | Graft | Diagnosis | Outcome |
|---|---|---|---|---|---|
| Khanna A., et al []11 | 1 | 53 | Whole live | HCV/HCC | – |
| Knechtle S.J., et al []12 | 1 | 52 | Whole live | HCV/Hemophilia A/HIV | Recurrent allograft hepatitis C |
| Seda Neto J., et al []13 | 1 | 2.8 | Whole liver | BA | – |
| Sakamoto J., et al []14 | 6 | 1.8–14 | Whole liver=5, right lobe graft=1 | BA=1, CHF=1 congenital protein C deficiency=1, FH=1, hepatoblastoma=1, mitochondrial hepatopathy=1 | None |
| Mohan N., et al []15 | 2 | 1.8–1.2 | Whole liver=2 | PSC=1, BA=1 | ACR |
| Seda Neto J., et al []16 | 11 | 0.5–5.7 | Whole liver=11 | BA=10, A-1ATD=1 | Bleeding, Reop-intra-abdominal clot, Reop-multiple perforation in the colon |
| Khanna A., et al []17 | 17 | 0.6–64.6 | Left lateral segments=2, whole liver=15 | PSC=5, PFIC=2,CF=1,CHF=2, embryonal sarcoma=1, A-1ATD=2, Caroli disease=1, neonatal hepatitis=1, HCC=1, PBC=1 | Ascitcs-paracentesis, biliary stricture, CRI, ACR, SFSS, Bile leak |
| Herden U., et al []18 | 8 | 0.3–62.3 | Whole liver=5, left lateral segments=2, right-extended segments=1 | PSC=2, BA=1, unclear cirrhosis=2, urea cycle disorder=1, glycogen storage disease type 1=1, hepatitis B/hepatitis D/hepatocellular carcinoma=1 | – |
| Khanna A., et al []2 | 4 | 1.4–20.7 | Left lateral segment=1, whole liver=3 | PA=1, CN-1=2, CPSD-1=1 | Hepatic artery thrombosis, TCMR, steatosis |
| Gao W., et al []19 | 3 | 0.6–1.4 | Whole liver=3 | BA=3 | None |
| ACR – acute cellular rejection; A-1ATD – α1-antitrypsin deficiency; BA – biliary atresia; CN – Crigler-Najjar syndrome; CPSD-1 – carbamoyl phosphate synthetase deficiency; CF – cystic fibrosis; CHF – chronic hepatic fibrosis; CRI – chronic renal injury; DLT – domino liver transplantation; FH – familial hypercholesterolemia; MSUD – maple syrup urine disease; PSC – primary sclerosing cholangitis; PFIC – progressive familial intrahepatic cholestasis; PBC – primary biliary cirrhosis; PA – propionic acidemia; SFSS – small-for-size syndrome. | |||||