Drug Overdose and Cardiovascular Deaths Among Deceased Organ Donors: Implications for Donor Utilization and Data Reporting

04 July 2023 : Original article

Michie A. Adjei

^1DEF, Steven A. Wisel^2DE, Irene K. Kim^2E, Justin A. Steggerda

^2ABCDEF*

DOI: 10.12659/AOT.940255

Ann Transplant 2023; 28:e940255

Background Material and Methods Results Discussion Conclusions References

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Table 3 Multivariable analysis of donor utilization by primary and expanded cause of death.

		DBD			DCD
		OR	95% CI	p-Value	OR	95% CI	p-Value
Expanded COD				<0.001			<0.001
	Trauma
	Cardiovascular	0.717	0.642–0.800		0.607	0.523–0.705
	CVA/Stroke	0.665	0.605–0.731		0.515	0.443–0.600
	Drug intoxication	1.308	1.100–1.555		0.754	0.603–0.914
	Anoxia (NOS)	0.867	0.739–1.017		0.765	0.640–0.914
	Other	0.649	0.467–0.902		0.449	0.346–0.583
Traditional COD				<0.001			<0.001
	Trauma
	CVA/Stroke	0.684	0.622–0.752		0.517	0.443–0.602
	Anoxia	0.848	0.765–0.940		0.687	0.597–0.791
	Other	0.586	0.473–0.726		0.517	0.415–0.645
Multivariable logistic regression analyses control for donor age, gender, race/ethnicity, body mass index, blood group; history of diabetes, hypertension, hepatitis C virus, hepatitis B virus; terminal labs including serum creatinine, sodium, INR, AST, ALT, bilirubin.

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