14 November 2023 : Original article
Evolution of Liver Transplantation Over the Last 2 Decades Based on a Single-Center Experience of 300 Cases
Akihiko Soyama1ABCDEF*, Takanobu Hara
1ABCDE, Hajime Matsushima 1BD, Hajime Imamura 1BD, Mampei Yamashita1BD, Tomohiko Adachi1BD, Satoshi Miuma2BD, Hisamitsu Miyaaki2BD, Kazuhiko Nakao2D, Susumu Eguchi1ABCD
DOI: 10.12659/AOT.941796
Ann Transplant 2023; 28:e941796
Table 1 Backgrounds of recipients and living liver donors.
| Era 1 | Era 2 | Era 3 | P-value | |
|---|---|---|---|---|
| Sex (male: female) | 59: 41 | 56: 44 | 56: 44 | 0.89 |
| Age | 54.5 (37.5–59) | 57 (50–62) | 58 (52–63.75) | 0.01 |
| MELD score | 17 (12–25) | 15 (12–22) | 18 (13–23) | 0.53 |
| Child-Pugh Score | 10 (8–11) | 10 (8–12) | 11 (9–12) | 0.06 |
| Operation duration (min) | 909 (785–1021) | 765 (689–851) | 748 (680–848) | <0.01 |
| Estimated intraoperative blood loss (g) | 6,950 3,262–14,362) | 5,100 (3,312–8,245) | 7195 (3,963–11,723) | 0.02 |
| Sex | 54: 46 | 56: 43 | 48: 40 | 0.93 |
| Age | 39 (29–51) | 39 (29–50) | 36.5 (30–51) | 0.92 |
| Graft type | ||||
| Left lobe with MHV (without MHV) | 34 (2) | 62 (1) | 56 (0) | <0.01 |
| Right lobe | 52 | 31 | 30 | |
| Left lateral | 9 | 1 | 1 | |
| Right lateral | 5 | 3 | 1 | |
| Approach in donor surgery | ||||
| Conventional open | 100 | 37 | 4 | <0.01 |
| Hybrid procedure | 0 | 62 | 84 | |
| Operation duration (min) | 425.5 (371–481) | 399 (354–456) | 392 (349–425) | <0.01 |
| Estimated intraoperative blood loss (g) | 700 (460–1045) | 550 (360–900) | 424 (252.5–648.5) | <0.01 |