13 February 2024 : Original article
A Retrospective Study of Long-Term Outcomes in 16 ABO-Incompatible Deceased Donor Pediatric Liver Transplants from a National Transplant Center at Helsinki University Hospital, Finland, 1987-2022
Timo Jahnukainen
1ABCDEFG*, Inna Sareneva2CD, Jouni Lauronen 2DE, Elisa Ylinen 1DE, Juuso Tainio 1BCE, Arno Nordin 3BDE, Maria Hukkinen 4BE, Mikko P. Pakarinen 4AE, Hannu Jalanko 1ADE
DOI: 10.12659/AOT.941929
Ann Transplant 2024; 29:e941929
Table 1 Patient demographics describing a cohort of 16 pediatric patients who received an ABO-incompatible liver transplant in Finland.
| Total number of patients | 16 |
| Age at transplantation, years (range) | 5.04 (0.52–15.4) |
| Male sex, n (%) | 9 (56.3) |
| Primary diagnosis, n (%) | |
| Biliary atresia | 7 (43.75) |
| Hepatoblastoma | 2 (12.5) |
| Metabolic disease | 5 (31.25) |
| Other | 2 (12.5) |
| Waiting time, days (range) | 27.5 (3–438) |
| Cause for ABO-I LT, n (%) | |
| Acute liver failure | 3 (18.75) |
| Malignancy | 2 (12.5) |
| Small body size and long waiting time | 4 (25) |
| Other (eg, recurrent severe infections) | 7 (43.75) |
| ABO blood group (donor ->recipient), n (%) | |
| A -> 0 | 8 (50) |
| B -> 0 | 4 (25) |
| A -> B | 1 (6.25) |
| B -> A | 0 |
| AB -> A | 2 (12.5) |
| AB -> B | 1 (6,25) |
| Re-transplantation, n (%) | 2 (12.5) |
| Follow-up time, months (range) | 147 (0.72–353) |
| Functioning graft, n (%)* | 14 (87.5) |
| Patients alive, n (%) | 10 (62.5) |
| Time from LT to death, months (range) | 94 (0.72–288) |
| Death <3 months after transplantation, n (%) | 3 (18.8) |
| * Including patients who died with functioning graft. ABO-I – ABO blood group incompatible, LT – liver transplantation. | |