13 February 2024>: Original Paper
A Retrospective Study of Long-Term Outcomes in 16 ABO-Incompatible Deceased Donor Pediatric Liver Transplants from a National Transplant Center at Helsinki University Hospital, Finland, 1987–2022
Timo Jahnukainen 1ABCDEFG* , Inna Sareneva 2CD , Jouni Lauronen 2DE , Elisa Ylinen 1DE , Juuso Tainio 1BCE , Arno Nordin 3BDE , Maria Hukkinen 4BE , Mikko P. Pakarinen 4AE , Hannu Jalanko 1ADEDOI: 10.12659/AOT.941929
Ann Transplant 2024; 29:e941929
Table 1 Patient demographics describing a cohort of 16 pediatric patients who received an ABO-incompatible liver transplant in Finland.
Total number of patients | 16 |
Age at transplantation, years (range) | 5.04 (0.52–15.4) |
Male sex, n (%) | 9 (56.3) |
Primary diagnosis, n (%) | |
Biliary atresia | 7 (43.75) |
Hepatoblastoma | 2 (12.5) |
Metabolic disease | 5 (31.25) |
Other | 2 (12.5) |
Waiting time, days (range) | 27.5 (3–438) |
Cause for ABO-I LT, n (%) | |
Acute liver failure | 3 (18.75) |
Malignancy | 2 (12.5) |
Small body size and long waiting time | 4 (25) |
Other (eg, recurrent severe infections) | 7 (43.75) |
ABO blood group (donor ->recipient), n (%) | |
A -> 0 | 8 (50) |
B -> 0 | 4 (25) |
A -> B | 1 (6.25) |
B -> A | 0 |
AB -> A | 2 (12.5) |
AB -> B | 1 (6,25) |
Re-transplantation, n (%) | 2 (12.5) |
Follow-up time, months (range) | 147 (0.72–353) |
Functioning graft, n (%)* | 14 (87.5) |
Patients alive, n (%) | 10 (62.5) |
Time from LT to death, months (range) | 94 (0.72–288) |
Death | 3 (18.8) |
* Including patients who died with functioning graft. ABO-I – ABO blood group incompatible, LT – liver transplantation. |