09 January 2024 : Original article
Retrospective Analysis of the Impact of High- and Low-Quality Donor Livers for Patients with High-Acuity Illness
Ron K. Varghese
1ABCDEFG*, Greta E. Handing 2ABCDFG, Ashley E. Montgomery 2ADE, Abbas A. Rana 3ACDE, John A. Goss 3AD
DOI: 10.12659/AOT.941931
Ann Transplant 2024; 29:e941931
Table 1 Recipient demographic characteristics.
| Type of liver in recipient | p-values | |||
|---|---|---|---|---|
| Low quality | Normal quality | High quality | ||
| No. patents | 1,985 | 5,955 | 1,983 | |
| Age | 51.4±11.6 | 51.0±11.8 | 51.6±11.8 | 0.095 |
| % Female | 43.5 | 39.9 | 34.8 | <0.001 |
| % African American | 18.0 | 18.1 | 9.73 | <0.001 |
| Height (cm) | 170.3±10.6 | 171.4±10.4 | 172.2±10.4 | <0.001 |
| Weight (kg) | 85.6±21.2 | 87.6±22.2 | 87.9±22.3 | <0.001 |
| INR | 3.35±3.78 | 3.14±1.74 | 3.17±2.23 | 0.004 |
| Creatine (mg/dL) | 2.40±1.52 | 2.44±1.59 | 2.42±1.57 | 0.69 |
| MELD | 39.9±4.5 | 40.1±4.3 | 40.0±4.2 | 0.31 |
| Cause of liver failure | ||||
| Acute hepatic necrosis | 1.54% | 4.82% | 1.52% | <0.001 |
| Cholestatic liver disease | 1.42% | 3.57% | 1.31% | <0.001 |
| Metabolic liver disease | 0.54% | 1.66% | 0.46% | <0.001 |
| Malignancy | 1.27% | 4.22% | 1.45% | <0.001 |
| Hepaptitis C | 1.55% | 5.19% | 1.82% | <0.001 |
| Hepatitis B | 0.54% | 1.31% | 0.42% | <0.001 |
| Alcoholic cirrhosis | 6.72% | 20.7% | 6.96% | <0.001 |