09 January 2024>: Original Paper
Retrospective Analysis of the Impact of High- and Low-Quality Donor Livers for Patients with High-Acuity Illness
Ron K. Varghese 1ABCDEFG* , Greta E. Handing 2ABCDFG , Ashley E. Montgomery 2ADE , Abbas A. Rana 3ACDE , John A. Goss 3ADDOI: 10.12659/AOT.941931
Ann Transplant 2024; 29:e941931
Table 3 Univariate and multivariate logistic regression of high- and normal-quality livers, compared with low-quality livers.
No. patients | Univariate | Multivariate (adjusted) | |||
---|---|---|---|---|---|
Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | ||
≥ | |||||
High-quality Liver (LDRI | 1,983 | 0.791 (0.654, 0.958) | 0.695 (0.549, 0.879) | ||
Normal-quality Liver (LDRI 1.33–1.86) | 5,955 | 1.021 (0.882, 1.182) | 0.78 | 0.858 (0.715, 1.028) | 0.10 |
Low-quality (LDRI >1.86) | 1,985 | 1 (Reference Range) | 1 (Reference Range) | ||
≥ | |||||
High-quality Liver (LDRI | 1,983 | 0.790 (0.653, 0.956) | 0.706 (0.558, 0.894) | ||
Normal-quality Liver (LDRI 1.33–1.86) | 5,955 | 1.017 (0.879, 1.178) | 0.82 | 0.856 (0.714, 1.026) | 0.09 |
Low-quality (LDRI >1.86) | 1,985 | 1.000 (Reference) | 1.000 (Reference) | ||
≥ | |||||
High-quality Liver (LDRI | 1,983 | 1.023 (0.905, 1.156) | 0.72 | 0.878 (0.747, 1.032) | 0.12 |
Normal-quality Liver (LDRI 1.33–1.86) | 5,955 | 0.915 (0.828, 1.011) | 0.08 | 0.845 (0.741, 0.965) | |
Low-quality (LDRI >1.86) | 1,985 | 1.000 (Reference) | 1.000 (Reference) | ||
≥ | |||||
High-quality Liver (LDRI | 1,822 | 1.000 (0.837, 1.195) | 0.99 | 1.021 (0.810, 1.286) | 0.86 |
Normal-quality Liver (LDRI 1.33–1.86) | 5,462 | 1.002 (0.867, 1.159) | 0.98 | 1.023 (0.847, 1.235) | 0.81 |
Low-quality (LDRI >1.86) | 1,827 | 1.000 (Reference) | 1.000 (Reference) | ||
≥ | |||||
High-quality Liver (LDRI | 1,836 | 0.805 (0.659, 0.984) | 0.703 (0.548, 0.900) | ||
Normal-quality Liver (LDRI 1.33–1.86) | 5,507 | 1.012 (0.867, 1.811) | 0.88 | 0.851 (0.703, 1.031) | 0.10 |
Low-quality (LDRI >1.86) | 1,834 | 1.000 (Reference) | 1.000 (Reference) | ||
≥ | |||||
High-quality Liver (LDRI | 1,983 | 0.926 (0.657, 1.305) | 0.66 | 0.852 (0.557, 1.302) | 0.46 |
Normal-quality Liver (LDRI 1.33–1.86) | 5,955 | 0.928 (0.707, 1.219) | 0.59 | 0.851 (0.608, 1.192) | 0.35 |
Low-quality (LDRI >1.86) | 1,985 | 1.000 (Reference) | 1.000 (Reference) | ||
* Significant p-values bolded. |