Allogeneic Hematopoietic Stem Cell Transplantation Can Improve Prognosis of Extramedullary Infiltration Positive t(8;21) Acute Myeloid Leukemia

Xiaokai Wang; Xuetong Xu; Hao Zhang; Wei Zhou; Dan Gong; Chengying Zhu; Dejun Zhou; Guofeng Chen

doi:10.12659/AOT.942197

19 December 2023 : Original article

Allogeneic Hematopoietic Stem Cell Transplantation Can Improve Prognosis of Extramedullary Infiltration Positive t(8;21) Acute Myeloid Leukemia

Xiaokai Wang^1BCDEF, Xuetong Xu^2BCDF, Hao Zhang^3CDF, Wei Zhou^45BC, Dan Gong^6BD, Chengying Zhu^78CF, Dejun Zhou^9ADFG, Guofeng Chen^9ABCDEFG*

DOI: 10.12659/AOT.942197

Ann Transplant 2023; 28:e942197

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Table 3 Multivariable models of pOS in t(8;21) AML patients with EMI at diagnosis.

	HR (95% CI)	P-value
Allo-HSCT^*
No	1.0
Yes	0.32 (0.13, 0.78)	0.0122
^* Multivariable models of allo-HSCT adjust for: sex and platelets. pOS – probability of overall survival; EMI – extramedullary infiltration; HR – hazard ratio; allo-HSCT – allogeneic hematopoietic stem cell transplantation.

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Allogeneic Hematopoietic Stem Cell Transplantation Can Improve Prognosis of Extramedullary Infiltration Positive t(8;21) Acute Myeloid Leukemia

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